CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027737
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fascin 
Protein Synonyms/Alias
  
Gene Name
 FSCN1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
478KVGGRYLKGDHAGVLubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Cytoplasm; Cytoskeleton. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 500 AA 
Protein Sequence
SASSTATMTA NGTAEAVQIQ FGLINCGNKY LTAEAFGFKV NASASSLKKK QIWTLEQPPD 60
EAGSAAVCLR SHLGRYLAAD KDGNVTCERE VPGPDCRFLI VAHDDGRWSL QSEAHRRYFG 120
GTEDRLSCFA QTVSPAEKWS VHIAMHPQVN IYSVTRKRYA HLSARPADEI AVDRDVPWGV 180
DSLITLAFQD QRYSVQTADH RFLRHDGRLV ARPEPATGYT LEFRSGKVAF RDCEGRYLAP 240
SGPSGTLKAG KATKVGKDEL FALEQSCAQV VLQAANERNV STRQGMDLSA NQDEETDQET 300
FQLEIDRDTK KCAFRTHTGK YWTLTATGGV QSTASSKNAS CYFDIEWRDR RITLRASNGK 360
FVTSKKNGQL AASVETAGDS ELFLMKLINR PIIVFRGEHG FIGCRKVTGT LDANRSSYDV 420
FQLEFNDGAY NIKDSTGKYW TVGSDSAVTS SGDTPVDFFF EFCDYNKVAI KVGGRYLKGD 480
HAGVLKASAE TVDPASLWEY 500 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0030175; C:filopodium; IEA:Compara.
 GO:0008144; F:drug binding; IEA:Compara.
 GO:0051017; P:actin filament bundle assembly; IEA:Compara.
 GO:0016477; P:cell migration; IEA:Compara. 
Interpro
 IPR008999; Actin_cross-linking.
 IPR010431; Fascin.
 IPR022768; Fascin-domain.
 IPR024703; Fascin_metazoans. 
Pfam
 PF06268; Fascin 
SMART
  
PROSITE
  
PRINTS