CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041613
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alcohol dehydrogenase class 4 mu/sigma chain 
Protein Synonyms/Alias
 RCG28864 
Gene Name
 Adh7 
Gene Synonyms/Alias
 rCG_28864 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
226IIGIDINKDKFQKALacetylation[1]
228GIDINKDKFQKALDVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Oxidoreductase; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
MDTAGKVIKC KAAVLWGTNQ PFSIEDIEVA PPKAKEVRVK ILATGICGTD DHVIKGTMVS 60
KFPVIVGHEA VGIVESVGEE VTTVRPGDKV IPLFLPQCRE CNPCRNPEGN LCIRSDLTGR 120
GVLADGTTRF TCKDKPVQHF MNTSTFTEYT VLDESSVAKI DAEAPPEKAC LIGCGFSTGY 180
GAAVKTAKVS PGSTCAVFGL GGVGLSVVMG CKAAGASRII GIDINKDKFQ KALDVGATEC 240
INPRDFTKPI SEVLSDMTGN TVQYTFEVIG RLETMVDALS SCHMNYGTSV VVGAPPSAKM 300
LSYDPMLLFT GRTWKGCVFG GWKSRDDVPK LVTEFLEKKF DLGQLITHTL PFHNISEGFE 360
LLYSGQSIRT VLTF 374 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005576; C:extracellular region; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IEA:Compara.
 GO:0004031; F:aldehyde oxidase activity; IEA:Compara.
 GO:0035276; F:ethanol binding; IEA:Compara.
 GO:0019841; F:retinol binding; IEA:Compara.
 GO:0004745; F:retinol dehydrogenase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006068; P:ethanol catabolic process; IEA:Compara.
 GO:0006069; P:ethanol oxidation; IEA:Compara.
 GO:1900116; P:extracellular negative regulation of signal transduction; IEA:Compara.
 GO:0010430; P:fatty acid omega-oxidation; IEA:Compara.
 GO:0009617; P:response to bacterium; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara.
 GO:0042573; P:retinoic acid metabolic process; IEA:Compara.
 GO:0042572; P:retinol metabolic process; IEA:Compara. 
Interpro
 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR002328; ADH_Zn_CS.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF08240; ADH_N
 PF00107; ADH_zinc_N 
SMART
  
PROSITE
 PS00059; ADH_ZINC 
PRINTS