UniProt Accession

 ARL8B_RAT; Q66HA6 

Genbank Protein ID

 BC081947 

Genbank Nucleotide ID

 AAH81947.1 

Protein Name

 ADP-ribosylation factor-like protein 8B 

Protein Synonyms/Alias

  

Gene Name

 Arl8b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
62	FNMRKVTKGNVTIKI	ubiquitination	[1]
68	TKGNVTIKIWDIGGQ	ubiquitination	[1]
141	LPNALDEKQLIEKMN	acetylation	[2]
141	LPNALDEKQLIEKMN	ubiquitination	[1]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity). 

Sequence Annotation

 NP_BIND 29 35 GTP (By similarity).
 NP_BIND 71 75 GTP (By similarity).
 NP_BIND 130 133 GTP (By similarity).  

Keyword

 Cell cycle; Cell division; Chromosome partition; Complete proteome; Cytoplasm; Cytoskeleton; Endosome; GTP-binding; Lysosome; Membrane; Mitosis; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 186 AA 

Protein Sequence

Gene Ontology

 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
 GO:0030496; C:midbody; IEA:Compara.
 GO:0051233; C:spindle midzone; IEA:Compara.
 GO:0019003; F:GDP binding; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 

Pfam

 PF00025; Arf 

SMART

 SM00177; ARF 

PROSITE

 PS51417; ARF 

PRINTS

 PR00328; SAR1GTPBP.