CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045445
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 H/ACA ribonucleoprotein complex subunit 4 
Protein Synonyms/Alias
  
Gene Name
 Dkc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
380ERDTYPRKWGLGPKAacetylation[1]
386RKWGLGPKASQKKQLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 509 AA 
Protein Sequence
MADAEAAMTF PKKHKKKKER KPLPEADVAV SGRGVFLIFL TCDNTAHGAM ASSPTLSQNF 60
DRLNVRTTHY TPIPCGSNPL KREIGEYVRT GFINLDKPSN PSSHEVVAWI RRILRVEKTG 120
HSGTLDPKVT GCLIVCIERA TRLVKSQQSA GKEYVGVVRL HNAIEGTAQL SRALETLTGA 180
LFQRPPLIAA VKRQLRVRTI YESRVVEYDP ERRLGVFWVS CEAGTYIRTL CVHLGLLLGV 240
GGQMQELRRV RSGVVGERDH MVTMHDVLDA QYLYDHHRDE SYLRRVVFPL EKLLTSHKRL 300
VMKDSAVNAI CYGAKIMLPG LLRYEDGIEV NQEVVVITTK GEAVCVAIAL MTTAVISTCD 360
HGVVAKIKRV IMERDTYPRK WGLGPKASQK KQLIKQGLLD KHGRPTDGTP ASWTRDYVDY 420
SDSSKKATAA EATPGPGVTA DAASIVKRKR DSDSDADEAT PTTTPRVKKE KKKKKEKADG 480
GEEAAEDGDG DATRKKKKKK ARAAEELSG 509 
Gene Ontology
 GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR012960; Dyskerin-like.
 IPR002501; PsdUridine_synth.
 IPR020103; PsdUridine_synth_cat_dom.
 IPR002478; PUA.
 IPR015947; PUA-like_domain.
 IPR004802; tRNA_PsdUridine_synth_B_fam.
 IPR004521; Uncharacterised_CHP00451. 
Pfam
 PF08068; DKCLD
 PF01472; PUA
 PF01509; TruB_N 
SMART
 SM00359; PUA 
PROSITE
 PS50890; PUA 
PRINTS