UniProt Accession

 C9JSG8_HUMAN; C9JSG8 

Genbank Protein ID

 AC144652; AC231970 

Genbank Nucleotide ID

  

Protein Name

 Insulin-induced gene 1 protein 

Protein Synonyms/Alias

  

Gene Name

 INSIG1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	SAAGLAAKVGEMINV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 123 AA 

Protein Sequence

Gene Ontology

 GO:0006695; P:cholesterol biosynthetic process; IEA:Compara.
 GO:0060363; P:cranial suture morphogenesis; IEA:Compara.
 GO:0042472; P:inner ear morphogenesis; IEA:Compara.
 GO:0042474; P:middle ear morphogenesis; IEA:Compara.
 GO:0045599; P:negative regulation of fat cell differentiation; IEA:Compara.
 GO:0045717; P:negative regulation of fatty acid biosynthetic process; IEA:Compara.
 GO:0010894; P:negative regulation of steroid biosynthetic process; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0006991; P:response to sterol depletion; IEA:Compara.
 GO:0006641; P:triglyceride metabolic process; IEA:Compara. 

Interpro

 IPR009904; INSIG.
 IPR025929; INSIG_fam. 

Pfam

 PF07281; INSIG 

SMART

  

PROSITE

  

PRINTS