CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027935
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein 70 
Protein Synonyms/Alias
 Heat shock protein 70, putative; Heat shock protein, putative 
Gene Name
 BiP 
Gene Synonyms/Alias
 TGGT1_087970; TGME49_111720; TGVEG_095730 
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
222AIAYGLDKKNEKTILacetylation[1]
334SETLTRAKFEELNSDacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Oxidoreductase; Reference proteome; Signal; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 668 AA 
Protein Sequence
MTAAKKLSLF SLAALFCLLS VATLRPVAAS DAEEGKVKDV VIGIDLGTTY SCVGVYRHGR 60
VDIIPNDQGN RITPSYVAFT DDDRKIGEAA KNEATINPTN TLFDVKRLIG RRFNEKEVQK 120
DKDLLPYEII NKDGKPYIRV MVKGEPKVLA PEEVSAMVLT KMKETAEQFL GKEVKNAVVT 180
VPAYFNDAQR QATKDAGAIA GLNVIRIINE PTAAAIAYGL DKKNEKTILV YDLGGGTFDV 240
SVLVIDNGVF EVLATSGDTH LGGEDFDQRV MDHFIKLVKK KYDKDLRTDK RGLQKLRREV 300
ERAKRALSSQ HQAKVEVENL MEGVDFSETL TRAKFEELNS DLFQKTLKPV KQVLEDADLQ 360
KSQVDEIVLV GGSTRIPKIQ QLIKDFFNGK EPNRGINPDE AVAYGAAVQA GILSGEGAQD 420
MVLLDVTPLT LGIETAGGVM AKIINKNTVI PTKKTQTFST YSDNQSAVLI QVYEGERPMT 480
KHNHLLGKFE LTGIPPAPRG VPQIEVTFDV DRNGILSVSA VDKGTGKSEK ITITNDKGRL 540
TPEEIERMIS EAEKFAEEDK KVKERVDARN ALEGYLHSMK TTVEDKDKLA DKIEEDDKKT 600
ILDKVTEAQE WLNTNPDADA EETRDKLKDV EAVCNPIISK VYGQSGGPGA GGAAGGADDD 660
DYGGHDEL 668 
Gene Ontology
 GO:0032440; F:2-alkenal reductase [NAD(P)] activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.