CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015301
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BTB/POZ domain-containing protein KCTD18 
Protein Synonyms/Alias
  
Gene Name
 KCTD18 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
363GTHLPPAKVLLSDKKubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
 DOMAIN 12 80 BTB.  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 426 AA 
Protein Sequence
MEGHKAEEEV LDVLRLNVGG CIYTARRESL CRFKDSMLAS MFSGRFPLKT DESGACVIDR 60
DGRLFKYLLD YLHGEVQIPT DEQTRIALQE EADYFGIPYP YSLSDHLANE METYSLRSNI 120
ELKKALTDFC DSYGLVCNKP TVWVLHYLNT SGASCESRII GVYATKTDGT DAIEKQLGGR 180
IHSKGIFKRE AGNNVQYIWS YYSVAELKKM MDAFDAWEGK GVSYWRVPHE LIECWTLEER 240
PLLGSLRHMA PIRKRRLITF NEADESVNYK TGPKPVRFLG PSTSTQIKVK NSASVTVSPA 300
SAIQTSAGAT ANRFQSGSRR KAAQRSAPSR ATALVGTGAP GHPQASPGAA SAENGGTHLP 360
PAKVLLSDKK PTPQRVIKLK RTPLCATAPC LPSPTATRQA NSLKPLPGEA ARALGVRTEN 420
GKNKGN 426 
Gene Ontology
 GO:0051260; P:protein homooligomerization; IEA:InterPro. 
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR003131; T1-type_BTB. 
Pfam
 PF02214; K_tetra 
SMART
 SM00225; BTB 
PROSITE
 PS50097; BTB 
PRINTS