CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005234
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sulfate adenylyltransferase subunit 1 
Protein Synonyms/Alias
 ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT 
Gene Name
 cysN 
Gene Synonyms/Alias
 b2751; JW2721 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
67SSLHNDSKRHGTQGEacetylation[1]
75RHGTQGEKLDLALLVacetylation[1]
108YFSTEKRKFIIADTPacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 May be the GTPase, regulating ATP sulfurylase activity. 
Sequence Annotation
 NP_BIND 34 41 GTP (By similarity).
 NP_BIND 113 117 GTP (By similarity).
 NP_BIND 168 171 GTP (By similarity).  
Keyword
 ATP-binding; Complete proteome; Direct protein sequencing; GTP-binding; Nucleotide-binding; Nucleotidyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MNTALAQQIA NEGGVEAWMI AQQHKSLLRF LTCGSVDDGK STLIGRLLHD TRQIYEDQLS 60
SLHNDSKRHG TQGEKLDLAL LVDGLQAERE QGITIDVAYR YFSTEKRKFI IADTPGHEQY 120
TRNMATGAST CELAILLIDA RKGVLDQTRR HSFISTLLGI KHLVVAINKM DLVDYSEETF 180
TRIREDYLTF AGQLPGNLDI RFVPLSALEG DNVASQSESM PWYSGPTLLE VLETVEIQRV 240
VDAQPMRFPV QYVNRPNLDF RGYAGTLASG RVEVGQRVKV LPSGVESNVA RIVTFDGDRE 300
EAFAGEAITL VLTDEIDISR GDLLLAADEA LPAVQSASVD VVWMAEQPLS PGQSYDIKIA 360
GKKTRARVDG IRYQVDINNL TQREVENLPL NGIGLVDLTF DEPLVLDRYQ QNPVTGGLIF 420
IDRLSNVTVG AGMVHEPVSQ ATAAPSEFSA FELELNALVR RHFPHWGARD LLGDK 475 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; ISS:EcoliWiki.
 GO:0003924; F:GTPase activity; IDA:EcoliWiki.
 GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:HAMAP.
 GO:0070814; P:hydrogen sulfide biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0000103; P:sulfate assimilation; IEA:HAMAP.
 GO:0006790; P:sulfur compound metabolic process; IMP:EcoliWiki. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR011779; SO4_adenylTrfase_lsu.
 IPR009001; Transl_elong_EF1A/Init_IF2_C.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2 
SMART
  
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.