CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030624
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ43948 fis, clone TESTI4014924, highly similar to Homo sapiens cytoplasmic FMR1 interacting protein 1 (CYFIP1), transcript variant 1, mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
178LCHAERRKDFVSEAYubiquitination[1]
574PKSGFDIKVPRRAVGubiquitination[2]
1055KMKRLESKYAPLHLVubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1255 AA 
Protein Sequence
MGPKHVLRQP GPSERHHPEV PAWTPRAGPP CWLCRQRWGW TLHPPGRGCP ALLLSEPRMA 60
AQVTLEDALS NVDLLEELPL PDQQPCIEPP PSSLLYQNEM LEEGQEYAVM LYTWRSCSRA 120
IPQVRCNEQP NRVEIYEKTV EVLEPEVTKL MNFMYFQRNA IERFCGEVRR LCHAERRKDF 180
VSEAYLITLG KFINMFAVLD ELKNMKCSVK NDHSAYKRAA QFLRKMADPQ SIQESQNLSM 240
FLANHNKITQ SLQQQLEVIS GYEELLADIV NLCVDYYENR MYLTPSEKHM LLKVMGFGLY 300
LMDGSVSNIY KLDAKKRINL SKIDKYFKQL QVVPLFGDMQ IELARYIKTS AHYEENKSRW 360
TCTSSGSSPQ YNICEQMIQI REDHMRFISE LARYSNSEVV TGSGRQEAQK TDAEYRKLFD 420
LALQGLQLLS QWSAHVMEVY SWKLVHPTDK YSNKDCPDSA EEYERATRYN YTSEEKFALV 480
EVIAMIKGLQ VLMGRMESVF NHAIRHTVYA ALQDFSQVTL REPLRQAIKK KKNVIQSVLQ 540
AIRKTVCDWE TGHEPFNDPA LRGEKDPKSG FDIKVPRRAV GPSSTQLYMV RTMLESLIAD 600
KSGSKKTLRS SLEGPTILDI EKFHRESFFY THLINFSETL QQCCDLSQLW FREFFLELTM 660
GRRIQFPIEM SMPWILTDHI LETKEASMME YVLYSLDLYN DSAHYALTRF NKQFLYDEIE 720
AEVNLCFDQF VYKLADQIFA YYKVMAGSLL LDKRLRSECK NQGATIHLPP SNRYETLLKQ 780
RHVQLLGRSI DLNRLITQRV SAAMYKSLEL AIGRFESEDL TSIVELDGLL EINRMTHKLL 840
SRYLTLDGFD AMFREANHNV SAPYGRITLH VFWELNYDFL PNYCYNGSTN RFVRTVLPFS 900
QEFQRDKQPN AQPQYLHGSK ALNLAYSSIY GSYRNFVGPP HFQVICRLLG YQGIAVVMEE 960
LLKVVKSLLQ GTILQYVKTL MEVMPKICRL PRHEYGSPGI LEFFHHQLKD IVEYAELKTV 1020
RFQNLHAAPF QNILPRVHVK EGERLDAKMK RLESKYAPLH LVPLIERLGT PQQIAIAREG 1080
DLLTKERLCC GLSMFEVILT RIRSFLDDPI WRGPLPSNGV MHVDECVEFH RLWSAMQFVY 1140
CIPVGTHEFT VEQCFGDGLH WAGCMIIVLL GQQRRFAVLD FCYHLLKVQK HDGKDEIIKN 1200
VPLKKMVERI RKFQILNDEI ITILDKYLKS GDGEGTPVEH VRCFQPPIHQ SLASS 1255 
Gene Ontology
  
Interpro
 IPR008081; Cytoplasmic_FMR1-int. 
Pfam
 PF05994; FragX_IP 
SMART
  
PROSITE
  
PRINTS
 PR01698; CYTOFMRPINTP.