| Tag | Content |
|---|
| CPLM ID | CPLM-009173 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and SAM domain-containing protein 1A |
Protein Synonyms/Alias | Odin |
Gene Name | Anks1a |
Gene Synonyms/Alias | Anks1; Kiaa0229; Odin |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 198 | DPTMRNNKFETPLDL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction. |
Sequence Annotation | REPEAT 75 104 ANK 1.
REPEAT 108 137 ANK 2.
REPEAT 165 194 ANK 3.
REPEAT 198 227 ANK 4.
REPEAT 231 260 ANK 5.
REPEAT 263 292 ANK 6.
DOMAIN 712 778 SAM 1.
DOMAIN 786 853 SAM 2.
DOMAIN 952 1107 PID.
MOD_RES 2 2 N-acetylglycine (By similarity).
MOD_RES 335 335 Phosphothreonine (By similarity).
MOD_RES 638 638 Phosphoserine (By similarity).
MOD_RES 640 640 Phosphoserine.
MOD_RES 642 642 Phosphoserine.
MOD_RES 644 644 Phosphoserine.
MOD_RES 663 663 Phosphoserine.
MOD_RES 677 677 Phosphoserine (By similarity).
MOD_RES 679 679 Phosphoserine.
MOD_RES 682 682 Phosphoserine.
MOD_RES 903 903 Phosphoserine. |
Keyword | Acetylation; Alternative splicing; ANK repeat; Cell projection; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1150 AA |
Protein Sequence | MGKEQELLEA ARTGHLPAVE KLLSGKRLSS GFGGGGGGSG SGGGSGGGGL GSSSHPLSSL 60
LSMWRGPNVN CVDSTGYTPL HHAALNGHRD VVEVLLRNDA LTNVADSKGC YPLHLAAWKG 120
DAQIVRLLIQ QGPSHTRVNE QNALEIRELK KYGPFDPYIN AKNNDNETAL HCAAQYGHTE 180
VVKALLEELT DPTMRNNKFE TPLDLAALYG RLEVVKLLLG AHPNLLSCST RKHTPLHLAA 240
RNGHKAVVQV LLDAGMDSNY QTEMGSALHE AALFGKTDVV QILLAAGIDV NIKDNRGLTA 300
LDTVRDLPSQ KSQQIAALIE DHMTGKRSVK EVDRTSTAQL PLLSNTDAIA PMSQGSMEKT 360
VTELILHFDT HADEEGPYEA LYNAVSCHSL DSTASGRSSD RDSMNKEAEA TGTRAAGVRP 420
RERPPPPAKP PPDEEEEERV DKKYFPLAAS EGLAVRPRIQ SSAPQEEEEH PYELLLTAET 480
KKLGTTDGRT EDHRQSGSGR SQDSVEGQDG QVPEQFSGLL HGSSPVCEVG QDPFQLLTAP 540
SQSHPESSQQ DACHEASMQL EEPGVQGTEP PQPGVPDQSK RVGLPAGLTA LASRTYLDAL 600
THTVPLRPAG AEEEDQSGPR SRAPPTSKPK AELKLSRSLS KSDSDLLTCS PTEDATMGSR 660
SESLSNCSIG KKRLEKSPSF ASEWDEIEKI MSSIGEGIDF SQEQQKISGS RTLEQSVGEW 720
LESIGLQQYE SKLLLNGFDD VRFLGSNVME EQDLREIGIS DPQHRRKLLQ AARSLPKVKA 780
LGYDGVSPTS VPSWLDSLGL QDYVHSFLSS GYSSIDTVKN LWELELVNVL KVHLLGHRKR 840
IIASLADRPY EEPPQKPPRF SQLRCQDLIS QTSSPLSQND SCTGRSADLL LPSADTSRRR 900
HDSLPDPGTA SRADRFRVQE EPSETKLTLR PPSLAAPYAP VQSWQHQPEK LIFESCGYEA 960
NYLGSMLIKD LRGTESTQDA CAKMRKSTEH MKKIPTIILS ITYKGVKFID ASNKNVIAEH 1020
EIRNISCAAQ DPEDLCTFAY ITKDLQTSHH YCHVFSTVDV NLTYEIILTL GQAFEVAYQL 1080
ALQAQKSRTM AASAASMIET KSSKPVPKPR VGMRKSALEP PDSDQEAPSH ASVSWIVDPK 1140
PDSKRSLSTN 1150 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0043005; C:neuron projection; IDA:UniProtKB. GO:0005634; C:nucleus; IEA:Compara. GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB. GO:0016322; P:neuron remodeling; IMP:UniProtKB. GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |