CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039555
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Long-chain-fatty-acid--CoA ligase 3 
Protein Synonyms/Alias
  
Gene Name
 ACSL3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68SKELLQTKLKDIVSLacetylation[1]
68SKELLQTKLKDIVSLubiquitination[2, 3]
88HIITVDGKPPTWSEFubiquitination[3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 141 AA 
Protein Sequence
MLGQKPKTNI AIFCETRAEW MIAAQACFMY NFQLVTLYAT LGGPAIVHAL NETEVTNIIT 60
SKELLQTKLK DIVSLVPRLR HIITVDGKPP TWSEFPKGII VHTMAAVEAL GAKASMENQP 120
HSKPLPSDIA VIMYTSGSTG L 141 
Gene Ontology
 GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:Compara.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0006633; P:fatty acid biosynthetic process; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara.
 GO:0014070; P:response to organic cyclic compound; IEA:Compara. 
Interpro
 IPR000873; AMP-dep_Synth/Lig. 
Pfam
 PF00501; AMP-binding 
SMART
  
PROSITE
  
PRINTS