UniProt Accession

 G3V2D2_HUMAN; G3V2D2 

Genbank Protein ID

 AC137834 

Genbank Nucleotide ID

  

Protein Name

 Serine hydroxymethyltransferase, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 SHMT2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
20	HGYMSDVKRISATSI	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 52 AA 

Protein Sequence

Gene Ontology

 GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0006544; P:glycine metabolic process; IEA:InterPro.
 GO:0006563; P:L-serine metabolic process; IEA:InterPro. 

Interpro

 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR001085; Ser_HO-MeTrfase. 

Pfam

 PF00464; SHMT 

SMART

  

PROSITE

  

PRINTS