| Tag | Content |
|---|
| CPLM ID | CPLM-004900 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytochrome P450 2C13, male-specific |
Protein Synonyms/Alias | CYPIIC13; Cytochrome P-450g; Cytochrome P450-G; Cytochrome P450-UT-5 |
Gene Name | Cyp2c13 |
Gene Synonyms/Alias | Cyp2c-13 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 129 | ATRHFTVKTLRNLGM | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. |
Sequence Annotation | METAL 435 435 Iron (heme axial ligand). |
Keyword | Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 490 AA |
Protein Sequence | MDPVVVLLLS LFFLLFLSLW RPSSGRGKLP PGPTPLPIIG NFFQVDMKDI RQSLTNFSKT 60
YGPVYTLYVG SQPTVVLHGY EALKEALVDH GEEFSGRGRL PICEKVAKGQ GIAFSHGNVW 120
KATRHFTVKT LRNLGMGKGT IEDKVQEEAK WLVKELKKTN GSPCDPQFIM GCAPGNVICS 180
IILQNRFDYE DKDFLNLIEK VNEAVKIISS PGIQVFNIFP ILLDYCPGNH NIYFKNHTWL 240
KSYLLEKIKE HEESLDVSNP RDFIDYFLIE RNQENANQWM NYTLEHLAIM VTDLFFAGIE 300
TVSSTMRFAL LLLMKYPHVT AKVQEEIDHV IGRHRSPCMQ DRSHMPYTNA MVHEVQRYID 360
IGPNGLLHEV TCDTKFRNYF IPKGTAVLTS LTSVLHDSKE FPNPEMFDPG HFLDENGNFK 420
KSDYFIPFSA GKRMCLGESL ARMELFLFLT TILQNFKLKS LVDPKDINTT PICSSLSSVP 480
PTFQMRFIPL 490 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0070330; F:aromatase activity; IEA:EC. GO:0009055; F:electron carrier activity; IEA:InterPro. GO:0020037; F:heme binding; IEA:InterPro. GO:0005506; F:iron ion binding; IEA:InterPro. GO:0004497; F:monooxygenase activity; TAS:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |