CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004572
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Homeobox protein Hox-B9 
Protein Synonyms/Alias
 Homeobox protein Hox-2.5; Homeobox protein Hox-2E 
Gene Name
 HOXB9 
Gene Synonyms/Alias
 HOX2E 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
130GAPGELLKQGTPEYSubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. 
Sequence Annotation
 DNA_BIND 185 244 Homeobox.  
Keyword
 Complete proteome; Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 250 AA 
Protein Sequence
MSISGTLSSY YVDSIISHES EDAPPAKFPS GQYASSRQPG HAEHLEFPSC SFQPKAPVFG 60
ASWAPLSPHA SGSLPSVYHP YIQPQGVPPA ESRYLRTWLE PAPRGEAAPG QGQAAVKAEP 120
LLGAPGELLK QGTPEYSLET SAGREAVLSN QRPGYGDNKI CEGSEDKERP DQTNPSANWL 180
HARSSRKKRC PYTKYQTLEL EKEFLFNMYL TRDRRHEVAR LLNLSERQVK IWFQNRRMKM 240
KKMNKEQGKE 250 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0009952; P:anterior/posterior pattern specification; IEA:Compara.
 GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.
 GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
 GO:0048706; P:embryonic skeletal system development; IEA:Compara.
 GO:0030879; P:mammary gland development; IEA:Compara.
 GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR017970; Homeobox_CS.
 IPR017112; Homeobox_Hox9.
 IPR020479; Homeobox_metazoa.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR006711; Hox9_activation_N. 
Pfam
 PF00046; Homeobox
 PF04617; Hox9_act 
SMART
 SM00389; HOX 
PROSITE
 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2 
PRINTS
 PR00024; HOMEOBOX.