CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044931
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 32 
Protein Synonyms/Alias
  
Gene Name
 USP32 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
271ERQKFCFKVFDVDRDmethylation[1]
702LVIEVRNKDMSWPEEacetylation[2]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Metal-binding; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 847 AA 
Protein Sequence
MRYVRRCVPL PGAPARVTDV ELKRLKDAFK RTCGLSYYMG QHCFIREVLG DGVPPKVAEV 60
IYCSFGGTSK GLHFNNLIVG LVLLTRGKDE EKAKYIFSLF SSESGNYVIR EEMERMLHVV 120
DGKVPDTLRK CFSEGEKVNY EKFRNWLFLN KDAFTFSRWL LSGGVYVTLT DDSDTPTFYQ 180
TLAGVTHLEE SDIIDLEKRY WLLKAQSRTG RFDLETFGPL VSPPIRPSLS EGLFNAFDEN 240
RDNHIDFKEI SCGLSACCRG PLAERQKFCF KVFDVDRDGV LSRVELRDMV VALLEVWKDN 300
RTDDIPELHM DLSDIVEGIL NAHDTTKMGH LTLEDYQIWS VKNVLANEFL NLLFQVCHIV 360
LGLRPATPEE EGQIIRGWLE RESRYGLQAG HNWFIISMQW WQQWKEYVKY DANPVVIEPS 420
SVLNGGKYSF GTAAHPMEQV EDRIGSSLSY VNTTEEKFSD NISTASEASE TAGSGFLYSA 480
TPGADVCFAR QHNTSDNNNQ CLLGANGNIL LHLNPQKPGA IDNQPLVTQE PVKATSLTLE 540
GGRLKRTPQL IHGRDYEMVP EPVWRALYHW YGANLALPRP VIKNSKTDIP ELELFPRYLL 600
FLRQQPATRT QQSNIWVNMG NVPSPNAPLK RVLAYTGCFS RMQTIKEIHE YLSQRLRIKE 660
EDMRLWLYNS ENYLTLLDDE DHKLEYLKIQ DEQHLVIEVR NKDMSWPEEM SFIANSSKID 720
RHKVPTEKGA TGLSNLGNTC FMNSSIQCVS NTQPLTQYFI SGRHLYELNR TNPIGMKGHM 780
AKCYGDLVQE LWSGTQKNVA PLKLRWTIAK YAPRFNGFQQ QDSQELLAFL LDGLHEDLNR 840
VHEKPYV 847 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR006615; Pept_C19_DUSP.
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19.
 IPR001125; Recoverin. 
Pfam
 PF06337; DUSP
 PF13202; EF_hand_3
 PF00443; UCH 
SMART
 SM00695; DUSP
 SM00054; EFh 
PROSITE
 PS51283; DUSP
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00972; UCH_2_1
 PS50235; UCH_2_3 
PRINTS
 PR00450; RECOVERIN.