UniProt Accession

 A2AQN7_MOUSE; A2AQN7 

Genbank Protein ID

 AL844852 

Genbank Nucleotide ID

  

Protein Name

 Glutathione synthetase 

Protein Synonyms/Alias

  

Gene Name

 Gss 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
66	ARLFDIYKQVLKEGI	acetylation	[1]
66	ARLFDIYKQVLKEGI	ubiquitination	[2]
70	DIYKQVLKEGIAQTV	ubiquitination	[2]
96	QCGADGSKALKQIEI	ubiquitination	[2]
99	ADGSKALKQIEINTI	ubiquitination	[2]
130	HVLNVLNKTKEASKI	acetylation	[1]
130	HVLNVLNKTKEASKI	ubiquitination	[2]
136	NKTKEASKILSNNPS	ubiquitination	[2]
144	ILSNNPSKGLALGIA	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 200 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004363; F:glutathione synthase activity; IDA:MGI.
 GO:0046686; P:response to cadmium ion; IDA:MGI. 

Interpro

 IPR004887; Glutathione_synth_subst-bd_euk.
 IPR005615; Glutathione_synthase_euk.
 IPR014049; Glutathione_synthase_N_euk.
 IPR016185; PreATP-grasp_dom. 

Pfam

 PF03917; GSH_synth_ATP
 PF03199; GSH_synthase 

SMART

  

PROSITE

  

PRINTS