CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038727
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dedicator of cytokinesis protein 9 
Protein Synonyms/Alias
  
Gene Name
 Dock9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
2009ANYREMAKELSDIMRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2058 AA 
Protein Sequence
MAQQQLPVST ETRKFTRALS KPGTAAELRQ SVSEVVRGSV LLAKPKLIEP LDYENVIVQK 60
KTQILNDCLR EMLLFPYDDF QTAILRRQGR YLRSTVPANA EEEAQSLFVT ECIKTYNSDW 120
HLVTYKYEDY SGEFRQLPNK VPKLDKLPVH VYEVDEEADK DEDAASLGSQ KGGITKHGWL 180
YKGNMNSAIS VTMRSFKRRF FHLIQLGDGS YNLNFYKDEK ISKEPKGSIF LDSCMGVIQN 240
NRVRRFAFEL KMQDKSSYLL AADSEAEMEE WVTVLNKILQ LNFEAAMQEK RNGDPHEDDE 300
QSKLEGSGSG LDSYLPELAK STREAEIKLK SESRVKLFYL DPDTQKLDFS SAEPEVKPFE 360
EKFGKRILVK CNDLSFNLQC CVAENEEGPT TNVEPFFVTL SLFDIKYNRK ISADFHVDLN 420
HFSVRQMLTP TSPALMNGGQ SPPAFQDALH TAMQYPKQGI FSVTCPHPDI FLVARIEKVL 480
QGSITHCAEP YMRSSDSSKV AQKVLKNAKQ ACQRLGQYRM PFAWAARTLF KDTSGNLDKN 540
ARFSAIYRQD SNKLSNDDML KLLADFRKPE KMAKLPVILG NLDITIDSVS CDFPNYLNSS 600
YIPMRQFETC SKSPITFEVE EFVPCIPKHT QPYTVYSNHL YVYPKYLKYD SQKSFAKARN 660
IAICIEFKDS DEEDSQPLKC IYGRPGGPVF TRSALAAVLH HQQNPEFYDE IKIELPAQLH 720
ERHHLLFTFF HVSCDNSTKG STKKKDAVET QVGFSWLPLL KDGRVLTSEQ HIPVSANLPS 780
GYLGYQELGM GRHYGPEVKW VEGGKPLLKI STHLVSTVYT QDQHLHNFFQ YCQKTESGAQ 840
ASGSELVKYL KSLHAMEGHV MIAFLPTILN QLFRVLTRAT QEEVAVNVTR VIIHVVAQCH 900
EEGLESHLRS YVKFAYKAEP YVASEYKTVH EELTKSMTTI LKPSADFLTS NKLLKYSWFF 960
FDVLIKSMAQ HLIENNKVKL LRNQRFPASY HHAVETVVNM LMPHITQKFR DNPEASKNAN 1020
HSLAVFIKRC FTFMDRGFVF KQINNYISCF APGDPKTLFE YKFEFLRVVC NHEHYIPLNL 1080
PMPFGKGRIQ RYQDLQLDYS LTDEFCRNHF LVGLLLREVG TALQEFREVR VIAISMLKNL 1140
LIKHSFDDRY NSRSHQARIA TLYLPLFGLL IENVQRINVR DVSPFPVNPG SIVKDEALAV 1200
PAGNPLMTPQ KGNTLDHSLH KDLLGAISGI ASPYTASTPN INSVRNADSR GSLISTDSGN 1260
SLPDRNPEKS NSLDKQQSGM LGNSVVRCDK LDQSEIKSLL MCFLYVLKSM SDDALFTYWN 1320
KASTAELMDF FTISEVCLHQ FQYMGKRYIA SVRKISSVLG ISVDNGYGHS EADVVHQSLL 1380
EANIATEVCL TALDTLSLFT LAFKNQLLAD HGHNPLMKKV FDVYLCFLQK HQSEMALKNV 1440
FTALRSLIYK FPSAFYEGRA DMCASLCYEV LKCCNSKLSS IRTEASQLLY FLMRNNFDYT 1500
GKKSFVRTHL QVIISVSQLI ADVVGIGGTR FQQSLSIINN CANSDRIIKH TSFSSDVKDL 1560
TKRIRTVLMA TAQMKEHEND PEMLVDLQYS LAKSYASTPE LRKTWLDSMA RIHVKNGDLS 1620
EAAMCYVHVT ALVAEYLTRK GMFRQGCTAF RVITPNIDEE ASMMEDVGMQ DVHFNEDVLM 1680
ELLEQCADGL WKAERYELIA DIYKLIIPIY EKRRDFERLA HLYDTLHRAY SKVTEVMHSG 1740
RRLLGTYFRV AFFGQGFFED EDGKEYIYKE PKLTPLSEIS QRLLKLYSDK FGSENVKMIQ 1800
DSGKVNPKDL DSKFAYIQVT HVTPFFDEKE LQERRTEFER CHNIRRFMFE MPFTQTGKRQ 1860
GGVEEQCKRR TILTAIHCFP YVKKRIPVMY QHHTDLNPIE VAIDEMSKKV AELRQLCSSA 1920
EVDMIKLQLK LQGSVSVQVN AGPLAYARAF LDDTNTKRYP DNKVKLLKEV FRQFVEACGQ 1980
ALAVNERLIK EDQLEYQEEM KANYREMAKE LSDIMREQIC PLEEKTSVLP NSLHIFNAIS 2040
GTPTSTVVQG LTSSSSVV 2058 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR027007; DHR-1_domain.
 IPR027357; DHR-2.
 IPR026791; DOCK.
 IPR010703; DOCK_C.
 IPR021816; DOCK_C/D_N.
 IPR026796; DOCK_D.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF06920; Ded_cyto
 PF14429; DOCK-C2
 PF11878; DUF3398
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS51650; DHR_1
 PS51651; DHR_2
 PS50003; PH_DOMAIN 
PRINTS