| Tag | Content |
|---|
| CPLM ID | CPLM-015252 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Integrator complex subunit 6 |
Protein Synonyms/Alias | Int6; DBI-1; Protein DDX26 |
Gene Name | Ints6 |
Gene Synonyms/Alias | Dbi1; Ddx26 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 694 | QAQPGLIKPLPLHKE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity). |
Sequence Annotation | DOMAIN 3 227 VWFA.
MOD_RES 800 800 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 883 AA |
Protein Sequence | MPILLFLIDT SASMNQRSHL GTTYLDTAKG AVETFMKLRA RDPASRGDRY MLVTFEEPPY 60
AIKAGWKENH ATFMNELKNL QAEGLTTLGQ SLRTAFDLLN LNRLVTGIDN YGQGRNPFFL 120
EPAIIITITD GSKLTTTSGV QDELHLPLNS PLPGSELTKE PFRWDQRLFA LVLRLPGTMS 180
VESEQLTGVP LDDSAITPMC EVTGGRSYSV CSPRMLNQCL ESLVQKVQSG VVINFEKAGP 240
DPPPAEEGQP DISRPFGSQP WHSCHKLIYV RPNPKTGVPI GHWPVPESFW PDQNSPTLPP 300
RTSHPVVKFS CTDCEPMVID KLPFDKYELE PSPLTQFILE RKSPQTCWQV YVSNSAKYNE 360
LGHPFGYLKA STALTCVNLF VMPYNYPVLL PLLDDLFKVH KAKPTLKWRQ SFESYLKTMP 420
PYYLGPLKKA VRMMGAPNLI ADSMEYGLSY SVISYLKKLS QQAKIESDRV IGSVGKKVVQ 480
ETGIKVRSRS HGLSMAHRKG FQVLQGISED VPHRLLDLNM KEYTGFQVAL LNKDLKPQTF 540
RNAYDIPRRN LLDHLTRMRS NLLKSTRKFL KGQDEDQVHS VPIAQMGNYQ EYLKQVPSPL 600
RELDPDQPRR LHTFGNPFKL DKKGMMIDEA DEFVAGPQNK HKRPGEPSMQ GIPKRRRCAS 660
PLLRGRRQSP AVNSHIGGKG PPAPMTQAQP GLIKPLPLHK EATNDSIVDD VVENHVADQL 720
SSDMTPNAMD TEFLTSPPNL LEPSTNHTEA LGHEHLGNND LTVGGFLENH EEPRNKEQSA 780
EENIPASSLN KGKKLMHCRS HEEVNTELKA QIMKEIRKPG RKYERIFTLL KHVQGSLQTR 840
LIFLQNVIKE ASRFKKRMLI EQLENFLDEI HRRANQINHI NSN 883 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |