CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010865
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integral membrane protein SED5 
Protein Synonyms/Alias
  
Gene Name
 SED5 
Gene Synonyms/Alias
 YLR026C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
35QRERLQEKESENFANubiquitination[1]
49NNTTGNGKSVSEFQKubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Required for vesicular transport between the endoplasmic reticulum and the Golgi complex. Acts as a target organelle soluble NSF attachment protein receptor (t-SNARE). 
Sequence Annotation
 DOMAIN 249 311 t-SNARE coiled-coil homology.  
Keyword
 3D-structure; Coiled coil; Complete proteome; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 340 AA 
Protein Sequence
MNIKDRTSEF QQSVLSYKKR NKNFREQQRE RLQEKESENF ANNTTGNGKS VSEFQKKASG 60
IAHEISSTAQ LLSKLAVLAK RKPMFNDNPV EIAELSFLIK RKIYAIEQSL VQLSQLKKTD 120
VNGNTSNQSS KQPSAVQHSK NVVNLLNTQM KNISGSFKDV LEERQRLEMA NKDRWQKLTT 180
DTGHAPADDQ TQSNHAADLT TYNNSNPFMT SLLDESSEKN NNSSNQGELS FPQNDSQLML 240
MEEGQLSNNV YLQERNRAVE TIESTIQEVG NLFQQLASMV QEQGEVIQRI DANVDDIDLN 300
ISGAQRELLK YFDRIKSNRW LAAKVFFIIF VFFVIWVLVN 340 
Gene Ontology
 GO:0005801; C:cis-Golgi network; IDA:SGD.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IDA:SGD.
 GO:0031201; C:SNARE complex; IDA:SGD.
 GO:0005484; F:SNAP receptor activity; IDA:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0048280; P:vesicle fusion with Golgi apparatus; IMP:SGD. 
Interpro
 IPR021538; Integral_membrane_Sed5p.
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF11416; Sed5p
 PF05739; SNARE
 PF00804; Syntaxin 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS