CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033783
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Interferon-induced protein with tetratricopeptide repeats 1 
Protein Synonyms/Alias
 Interferon-induced protein with tetratricopeptide repeats 1, isoform CRA_b 
Gene Name
 IFIT1 
Gene Synonyms/Alias
 hCG_24571 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
120EEGWALLKCGGKNYEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 447 AA 
Protein Sequence
MPDLENRVLD QIEFLDTKYS VGIHNLLAYV KHLKGQNEEA LKSLKEAENL MQEEHDNQAN 60
VRSLVTWGNF AWMYYHMGRL AEAQTYLDKV ENICKKLSNP FRYRMECPEI DCEEGWALLK 120
CGGKNYERAK ACFEKVLEVD PENPESSAGY AISAYRLDGF KLATKNHKPF SLLPLRQAVR 180
LNPDNGYIKV LLALKLQDEG QEAEGEKYIE EALANMSSQT YVFRYAAKFY RRKGSVDKAL 240
ELLKKALQET PTSVLLHHQI GLCYKAQMIQ IKEATKGQPR GQNREKLDKM IRSAIFHFES 300
AVEKKPTFEV AHLDLARMYI EAGNHRKAEE NFQKLLCMKP VVEETMQDIH FHYGRFQEFQ 360
KKSDVNAIIH YLKAIKIEQA SLTRDKSINS LKKLVLRKLR RKALDLESLS LLGFVYKLEG 420
NMNEALEYYE RALRLAADFE NSVRQGP 447 
Gene Ontology
 GO:0071360; P:cellular response to exogenous dsRNA; IEA:InterPro.
 GO:0071357; P:cellular response to type I interferon; IEA:InterPro.
 GO:0050688; P:regulation of defense response to virus; IEA:InterPro.
 GO:0009615; P:response to virus; IEA:InterPro. 
Interpro
 IPR024121; Interferon-induced_IFIT1.
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1
 PF07719; TPR_2 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS