CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004203
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L7 
Protein Synonyms/Alias
  
Gene Name
 Rpl7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
10AVPEKKKKVATVPGTubiquitination[1]
19ATVPGTLKKKVPAGPubiquitination[1]
62LRKKFALKTLRKARRubiquitination[1]
99RMARMARKAGNFYVPubiquitination[1]
110FYVPAEPKLAFVIRIubiquitination[1]
146IFNGTFVKLNKASINubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity). 
Sequence Annotation
 REPEAT 7 18 1.
 REPEAT 19 29 2.
 REPEAT 30 40 3.
 REPEAT 41 52 4.
 REPEAT 53 64 5.
 REPEAT 65 76 6.
 REGION 7 76 6 X 12 AA tandem repeats.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 146 146 N6-acetyllysine (By similarity).
 MOD_RES 161 161 Phosphotyrosine (By similarity).  
Keyword
 Acetylation; Complete proteome; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 270 AA 
Protein Sequence
MEAVPEKKKK VATVPGTLKK KVPAGPKTLK KKVPAVPETL KKKRRNFAEL KVKRLRKKFA 60
LKTLRKARRK LIYEKAKHYH KEYRQMYRTE IRMARMARKA GNFYVPAEPK LAFVIRIRGI 120
NGVSPKVRKV LQLLRLRQIF NGTFVKLNKA SINMLRIVEP YIAWGYPNLK SVNELIYKRG 180
YGKINKKRIA LTDNSLIARS LGKFGIICME DLIHEIYTVG KRFKEANNFL WPFKLSSPRG 240
GMKKKTTHFV EGGDAGNRED QINRLIRRMN 270 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; IDA:MGI.
 GO:0003677; F:DNA binding; ISO:MGI.
 GO:0003729; F:mRNA binding; ISO:MGI.
 GO:0042803; F:protein homodimerization activity; ISO:MGI.
 GO:0003735; F:structural constituent of ribosome; IC:MGI.
 GO:0042273; P:ribosomal large subunit biogenesis; IEA:Compara.
 GO:0006364; P:rRNA processing; IEA:Compara.
 GO:0006412; P:translation; IC:MGI. 
Interpro
 IPR018038; Ribosomal_L30_CS.
 IPR016082; Ribosomal_L30_ferredoxin-like.
 IPR012988; Ribosomal_L30_N.
 IPR005998; Ribosomal_L7_euk. 
Pfam
 PF00327; Ribosomal_L30
 PF08079; Ribosomal_L30_N 
SMART
  
PROSITE
 PS00634; RIBOSOMAL_L30 
PRINTS