CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012807
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA-binding protein cabeza 
Protein Synonyms/Alias
 P19; Sarcoma-associated RNA-binding fly homolog 
Gene Name
 caz 
Gene Synonyms/Alias
 SARFH; CG3606 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
43EPPPNYGKQGGGYDSacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 May participate in a function common to the expression of most genes transcribed by RNA polymerase II. 
Sequence Annotation
 DOMAIN 120 206 RRM.
 ZN_FING 275 304 RanBP2-type.  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; RNA-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 399 AA 
Protein Sequence
MERGGYGGGS GQGYNNFAVP PPNYQQMPNK TGNYNEPPPN YGKQGGGYDS GSGHRGSGGS 60
GNGGGGGGSW NDRGGNSYGN GGASKDSYNK GHGGYSGGGG GGGGGGGGGS GGNDMITQED 120
TIFVSGMDPS TTEQDIETHF GAIGIIKKDK RTMKPKIWLY KNKETGASKG EATVTYDDTN 180
AAQSAIEWFD GRDFNGNAIK VSLAQRQNNW NKGGGGGGGG GGRGGFGGRR GGGGGGGGGG 240
GGGGRFDRGG GGGGGRYDRG GGGGGGGGGG NVQPRDGDWK CNSCNNTNFA WRNECNRCKT 300
PKGDDEGSSG GGGGGGYGGG GGGGGYDRGN DRGSGGGGYH NRDRGGNSQG GGGGGGGGGG 360
YSRFNDNNGG GRGGRGGGGG NRRDGGPMRN DGGMRSRPY 399 
Gene Ontology
 GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.
 GO:0005654; C:nucleoplasm; IDA:FlyBase.
 GO:0003729; F:mRNA binding; ISS:FlyBase.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008344; P:adult locomotory behavior; IMP:FlyBase.
 GO:0048749; P:compound eye development; IMP:FlyBase.
 GO:0008345; P:larval locomotory behavior; IMP:FlyBase.
 GO:0000398; P:mRNA splicing, via spliceosome; IC:FlyBase.
 GO:2000673; P:positive regulation of motor neuron apoptotic process; IMP:FlyBase. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR001876; Znf_RanBP2. 
Pfam
 PF00076; RRM_1
 PF00641; zf-RanBP 
SMART
 SM00360; RRM
 SM00547; ZnF_RBZ 
PROSITE
 PS50102; RRM
 PS01358; ZF_RANBP2_1
 PS50199; ZF_RANBP2_2 
PRINTS