CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043267
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Bifunctional apoptosis regulator 
Protein Synonyms/Alias
  
Gene Name
 BFAR 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
76ECPECREKWEGFPKVubiquitination[1]
82EKWEGFPKVSILLRLubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 325 AA 
Protein Sequence
MEEPQKSYVN TMDLERDEPL KSTGPQISVS EFSCHCCYDI LVNPTTLNCG HSFCRHCLAL 60
WWASSKKTEC PECREKWEGF PKVSILLRLL LTLTEEEFSK TPYTIENSSH RRAILMELER 120
VKALGVKPPQ NLWEYKAVNP GRSLFLLYAL KSSPRLSLLY LYLFDYTDTF LPFIHTICPL 180
QEDSSGEDIV TKLLDLKEPT WKQWREFLVK YSFLPYQLIA EFAWDWLEVH YWTSRFLIIN 240
AMLLSVLELF SFWRIWSRSE LKTVPQRMWS HFWKVSTQGL FVAMFWPLIP QFVCNCLFYW 300
ALYFNPIINI DLVVKELRRL ETQVL 325 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS