CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032642
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dynein beta chain, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_061370 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
2799KTLQMGVKDICRAEKacetylation[1]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 4439 AA 
Protein Sequence
MSAVGGYGSG RPTETGESGF LENGSTERVL LDADACAAWL KPRLPFSTFD AEEHWSPAYG 60
ESFLAWCQDA TQARLFVHFD KPADGAPHLR FVRNRIPEDV RSAEIDEFVF FAKRTSTPIT 120
AVNLNEQVFF TCIRGDMLKY LLTLIGGVYV PLSMKEHGWP ETIRKDFTGQ LQRFLATVTE 180
NIYKAKGATL LYVPIDDLSD LEVALKDKDL VQRLEATVIH WTRQIKEVMM VQDTTQEADN 240
TGHLDEIRFW RERAVNFSRL MEQFKSQAVQ RIFQLLERSK STYLKQFRVV QADVEQASLE 300
AEDNLRFLSA LEKPSEKLAQ AKPKEIPSIL RQLLNSVRMI WSTSTYYNTS DRISGLLRKI 360
SSEVIKRCQA AIDLNSIWSG VVDDAMTSLE QSIECGRAWK GLYQPMCKLV KRYSQGREWD 420
FPEGAVFAEI DAFVQRCCDL LEVCECQRHF NTRAQQIVLP LFGGLRCKEV TRSIYEIEDS 480
FAKGLRRLRD LDYFVLDVKA ARWHDDFAVF KNQVKDLEFM YKNVITSALE GVQTVDGACQ 540
VYDAFYLLAK RTRIKKFLEK KSADVWTLFI QDLTLVKRQF EYIRKNPTQS LSVPYQHPPH 600
AGLGLWARGL ILKIQNQMDT LDSMHYLPSC REAEVARENF NSIRSMLVSF TEQSFEEWTQ 660
ELNALDGNTA ALAKSLERPL LIRADANILS RGRGGQLESN FDKTLLKNLQ EAYFWQKMHN 720
QGINLPYAAH EMLRQRDKLM ALREHVLRVV REYNLTLETI APDERRLFQQ HIKTLDKKVA 780
PGIQKLTWNS KGIKEFFVRD TCRECQVVYG FVRRFQTNHQ TILNHCKGIS ELHFLSIDRR 840
KIYADEEFRQ AQAAKKVEME AYLSEAHAGI SAVLQDSQRL FEDHPPEIQR EWKMYVEKVD 900
KRVGDALKKA VRTSLQELSK VLNPADGKNS TVDVAPLFKV YAVLDSHNRM DFKPTMADLK 960
ELLQVVCKDL CLTLHVVPRL WEYLQTLKER DSEFPDDDNS EREEHRAEGE PKAEGKKQLS 1020
TFYAMISKDD DCVRIVVQIM KGMANCALKL QERLKWWHNN YHPIVSQNKE DIIRKYARTE 1080
RPLPVICTNI QRYKELQADI QQEEFKITLC FLEADFTLLK QALMKHCQQW QAQLVAYLHR 1140
NALLEADNLL AYFTSNAERL RQVPTTTEEI REKLNLWHRC KADIPYLEDR IRPIEEQFAK 1200
LAELDVQIPE FEDTKLQSLR PRAQQFESML EETEVMLNKY VLKKATDIEM LMQAVGKQAA 1260
DLFKQFSASA PFDGVAFNYD SQIAFNTIAL YRGEVQKLRD SEERLKPKLE FFELEAMQYK 1320
ELAKMESDFQ MLTDIWTLAE QWESEWNRIK MKALYDLSMS DLELTADAFQ GRLVKMKEIR 1380
TWPIWRKCQQ EVDQFRKGLP LISNLRSPAL RERHWLRLKK EVAEPFDPHS KEFTLNSVVQ 1440
LDLVRRADLI GRLADEARKE FKIETALQEI ASTWKNMQLD IGPHKDMLLK LKSNDDLFNI 1500
LEENILALSV MKSNQYHLPF KDEVDYWETT LAHISEAIEW LLQVQKQWIY LENVFRGSDD 1560
IRSMLPQEAT VFDGVHVMFV GLLFRLQADT SVLRACTIPG LVADLNEMND KLDRLQKSLD 1620
DYLENKRQEF PRFYFLSNSD LLEILGHSKE PDQIQKHIKK IFEGIKLLDL IPPGEQTKAW 1680
DAEGMIAPDG EKVKFQPKNV VLEGPVEVWL NKVEKGMRET LKRLLVSTHQ ANLAKGTKKE 1740
RWVLECCGQL AITSSQIAWT SDTENALRKI AKGNKNALKQ LKKQQCRYLS KLIDLVRKPL 1800
TPVEQSKIVS LITIEVHARD VQEKLIQMRC ENDNCFVWKS QLRFELRDDI VEDKQGNSSS 1860
APGLGVMACH VRQTETSLPY GYEYQGNNGR LVITPLTDKC YMTLTMALHL KLGGSPQGPA 1920
GTGKTETVRD LGKGVAKLVL VFNCSDALDY ISLGRIFSGL AQSGTWGCFD EFNRIEIEVL 1980
SVVAQQISVI QHALRFQNFK FLFEGHRVRL DPYCGIFITM NPGYAGRTEL PDNLTSLFRP 2040
VAMMVPDLVM ICEITLMAEG FEDARVLSKK IITLYQLMTQ QLSKQDHYDF GLRAIRAVLS 2100
RAGQIRRSGG DQTEQDVLIR AILDMNASRT VTDDSFLFNA LMSDLFPETD LTQFPNSDPV 2160
LRRALDWAME ADGLQKVDHI AVKATQLFLT MQTRHGNMLV GKSLTGKTTT WSILQKALCH 2220
LNATGTPDFE AVKTWVINPK SLDVNELYGR FNIQTLEWTD GILSAIVREV CQDTRLTHKW 2280
IILDGPVDPL WIESMNSLLD DNKTLTLING DRIAMPPQVS LLFEVENLAA ASPATVSRVG 2340
MVYMDPGDLD WKPYVQSWLA RNFQNVEMQT FVAQLFGKYL DKVLKVRGEC TELVPITDMN 2400
GVISLCKLYE VFAGRLTPDL QGEKQFSMVE KVFAFSVVWS LGASVDAASR PLVDRCIRQI 2460
EPSFPPGHLV YDYFLNYEKQ DWKLWEDRLP SQYRPFEGTP FHKIIVPTVD VLRNGHVLSG 2520
LILHRRHALC VGQTGTGKTS SILTTVMQEL PESTHATLII NFSAQTSSKK TQQIIEGKLE 2580
KRVKDKYGPP GNKRLACFVD DLNLPRKDTF GSQPPLELLR QLIDYGCWYD RGKQTVKYVQ 2640
DTQILAAMGP PGGGRSVIPA RLQSRFNLLN FTEPDEQQVK RIFNTLAIHK FSDFREDIKT 2700
NAENLAAATI SLFEQVREQF LPKPDKPHYL FNMRDMSRVF QGIYQAEPHV YEDRDSILRL 2760
WLHECMRVFH DRLASEEDRG ELLHILDGVL DKTLQMGVKD ICRAEKDLIF VALPFDSTPG 2820
AEASYDEVSD KQMLKTFLTA KLEEYNERSL RGRMPVVLFK DAIEHCCRIF RILCLPNGHA 2880
TLVGVGGSGR HSLTLFACFL ADQQCFQIEV NRDYGHPEFQ EDLKKLYNAT GVDGKRTTFL 2940
LSDANILSES FIEDVHNMLS SGEVSNLFTT DEFSAISAEL EKAAKAAGVN PSNRDAMHDF 3000
FLSRVRENLH IVFCVRPIGQ QLRDYCRNYP GVVNNTTIDW FFPWPEDALT EVAATFLVDS 3060
TVEVEHRQSI TQVVSAAHAS VIAESERMFA EMKRRNYVTP TKFLELVQGY IRLYREKTEE 3120
VQELVHKLTV GLHKLVETRA QVEVMGTELE RKKEIVAKKQ TECQDLLVVI VEKRSVADEQ 3180
KKQVEADSDR ISKEEVETKI LSEDARRDLA KAMPALEAAI DALEKLDKKS VAEVKAYTKP 3240
PDLVVKTMAA VMTVMEKTPS WAQAKVELND PSFLTKVKNF DKDSISNNTL KKIEKFTKDP 3300
TFAPNNVLKV SRAAGALCMW VHAMQMYAEV YREVEPKRLR LRLAEEQLEK KQMDLLASTQ 3360
RLQDIQQRLE ELKDQYNASI RTKDELNASA EELKLKMERA ESLIAGLAGE RDRWEISLAQ 3420
STEKLKALPG DCLVAAAFMA YAGPFNADYR KRLVTQSWVP LVSTFNIPHN PNFDFADFLA 3480
RPIDVRQWNL QGLPSDRFST ENGVLVTMSR RWPLMIDPQN QATKWIRRLE AANDLRLVDP 3540
ETRNYMRVIT TAVENGKPLL MERVQNGIDP SLESLLAQRI TDVGGSPSIR IGDVVVRYNT 3600
NFRFYLTTKM SNPHFMPEIA SSVNLVNFIV KEDGLTAQLL AIVVMKEEPR LEEQKNELVV 3660
SLAEGRRRLQ DLEDEILRLL TNSQGSLLDD VELITALQES KSIAGEVTRQ IEVSEQTMQK 3720
IDQARDAYKP CGIRASVLFF VLHDLIVADP MYQFSLDSYV ELFVSSIEKT KEDNAMTTSV 3780
EEHVQILNSY HTVAVYRNAC LGLFEKHKLL LSLHLTTSIL QSRGQLNREE YQFLLTGASV 3840
ADRRNQAQNP DPDWISESVW DSICELSKLQ NFQGFQTSYE QSLRDWRKWY ATVEPERESL 3900
PGEWQTRLDS LQRLLIIRSL RPDRFLPAAT RFIAETMDGR FVDSPPLNLE AVFNASKNTI 3960
PLIFVLSKVD PTGQLMALAS AKNVQAIAVA LGQGQSARAE KLIREGARHG FWVFLANCHL 4020
ALSWLPTMEK IIEEVTESDP HENFRLWLSS EPHPDFPIAL LQRSTKITTE PPKGLKSNLQ 4080
RLLLQHTDED LNRVKCGDDR YRRLFFALCW LHAVLLERRK FKSVGWNVPY DFNDSDFLVS 4140
DNILSIYVEQ YSNDMPWEAL RYMIADACYG GRVTDDKDLR LLRVYCADFF CPQALQPDFS 4200
FSSSGTYYIP EDTTLTGLSN YVRDLSVIDP PEAFSQHVNA EISSQIADAE SLLSTLLLLQ 4260
PPGTTVQSAG GAGKPEDQVY RICETVEQEW PADIDYPLIV ARGEGDVSPL RVVLLQEVQR 4320
FNRLLQFVRE SLGSLKKGLV GLAVMSDEVE LVMQALEKSK VPEAWKFAYP SVKSLSSWVL 4380
DLKERVEFMS KWGLERIPKV FWLGGFTYPS GFLTALLQQF ARRNTLSIDT LNFDFLVQV 4439 
Gene Ontology
 GO:0005858; C:axonemal dynein complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0001539; P:ciliary or flagellar motility; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR011704; ATPase_dyneun-rel_AAA.
 IPR026983; DHC_fam.
 IPR026976; DNAH2.
 IPR024743; Dynein_HC_stalk.
 IPR024317; Dynein_heavy_chain_D4_dom.
 IPR004273; Dynein_heavy_dom.
 IPR013594; Dynein_heavy_dom-1.
 IPR013602; Dynein_heavy_dom-2.
 IPR027417; P-loop_NTPase. 
Pfam
 PF07728; AAA_5
 PF12780; AAA_8
 PF08385; DHC_N1
 PF08393; DHC_N2
 PF03028; Dynein_heavy
 PF12777; MT 
SMART
  
PROSITE
  
PRINTS