CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016664
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial 2-oxodicarboxylate carrier 
Protein Synonyms/Alias
 Solute carrier family 25 member 21 
Gene Name
 Slc25a21 
Gene Synonyms/Alias
 Odc 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
89ETPKRAVKFSTFELYacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate (By similarity). 
Sequence Annotation
 REPEAT 10 99 Solcar 1.
 REPEAT 106 195 Solcar 2.
 REPEAT 204 293 Solcar 3.  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
MSASNVSLLH ETSRQVAAGG SAGLVEICLM HPLDVVKTRF QVQRSVTDPQ SYRTVRGSFQ 60
MIFRTEGLFG FYKGIIPPIL AETPKRAVKF STFELYKKFL GYMSLSPGLT FLIAGLGSGL 120
TEAVVVNPFE VVKVGLQVNR NLFKEQPSTF AYARQIIKKE GLGFQGLNKG LTATLGRHGI 180
FNMVYFGFYH NVKNIIPSSK DPTLEFLRKF GIGFVSGTMG SVFNIPFDVA KSRIQGPQPV 240
PGEIKYRSCF KTMEMIYREE GILALYKGLV PKVMRLGPGG GVMLLVYEYT YAWLQENW 298 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS