CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042718
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phospholipase A-2-activating protein 
Protein Synonyms/Alias
  
Gene Name
 PLAA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
240DILRLSIKHPSVNENubiquitination[1, 2, 3, 4]
270NLLNPKGKPANQLLAubiquitination[3, 5]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 290 AA 
Protein Sequence
XLGDINAEQL PGREHLNEPG TREGQTRLIR DGEKVEAYQW SVSEGRWIKI GDVVGSSGAN 60
QQTSGKVLYE GKEFDYVFSI DVNEGGPSYK LPYNTSDDPW LTAYNFLQKN DLNPMFLDQV 120
AKFIIDNTKG QMLGLGNPSF SDPFTGGGRY VPGSSGSSNT LPTADPFTGA GRYVPGSASM 180
GTTMAGVDPF TGNSAYRSAA SKTMNIYFPK KEAVTFDQAN PTQILDIVFP ALDILRLSIK 240
HPSVNENFCN EKEGAQFSSH LINLLNPKGK PANQLLALRT FCNCFVGQAG 290 
Gene Ontology
  
Interpro
 IPR015155; PLAA_fam_Ub-bd_PFU.
 IPR013535; PUL. 
Pfam
 PF09070; PFU
 PF08324; PUL 
SMART
  
PROSITE
 PS51394; PFU
 PS51396; PUL 
PRINTS