CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011234
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SNF1 protein kinase subunit beta-3 
Protein Synonyms/Alias
 Glucose repression protein GAL83; Protein SPM1 
Gene Name
 GAL83 
Gene Synonyms/Alias
 SPM1; YER027C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
287RIALEIEKEPDDMGDubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Beta subunit of the SNF1 kinase complex, which is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation. Has a structural role, mediating heterotrimer formation, and a regulatory role, defining carbon source-regulated subcellular location and substrate specificity of the SNF1 kinase complex. Promotes the relocalization of the SNF1 kinase complex to the nucleus upon shift to nonfermentable carbon sources. 
Sequence Annotation
 REGION 152 342 Kinase-interacting sequence (KIS);
 REGION 343 417 Association with SNF1 kinase complex
 MOD_RES 12 12 Phosphoserine.
 MOD_RES 21 21 Phosphoserine.
 MOD_RES 44 44 Phosphoserine.
 MOD_RES 135 135 Phosphoserine.
 MOD_RES 276 276 Phosphoserine.
 MOD_RES 279 279 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 417 AA 
Protein Sequence
MAGDNPENKD ASMLDVSDAA SNTTINGKHS ADSTNEASLA YTFSQMNVDN PNELEPQHPL 60
RHKSSLIFND DDDDEIPPYS NHAENGSGET FDSDDDIDAS SSSSIDSNEG DIHDADMTGN 120
TLQKMDYQPS QQPDSLQNQG FQQQQEQQQG TVEGKKGRAM MFPVDITWQQ GGNKVYVTGS 180
FTGWRKMIGL VPVPGQPGLM HVKLQLPPGT HRFRFIVDNE LRFSDYLPTA TDQMGNFVNY 240
MEVSAPPDWG NEPQQHLAEK KANHVDDSKL SKRPMSARSR IALEIEKEPD DMGDGYTRFH 300
DETPAKPNLE YTQDIPAVFT DPNVMEQYYL TLDQQQNNHQ NMAWLTPPQL PPHLENVILN 360
SYSNAQTDNT SGALPIPNHV ILNHLATSSI KHNTLCVASI VRYKQKYVTQ ILYTPLQ 417 
Gene Ontology
 GO:0031588; C:AMP-activated protein kinase complex; IDA:SGD.
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005641; C:nuclear envelope lumen; IDA:SGD.
 GO:0007155; P:cell adhesion; IMP:SGD.
 GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.
 GO:0006468; P:protein phosphorylation; IGI:SGD.
 GO:0043254; P:regulation of protein complex assembly; IGI:SGD.
 GO:0007165; P:signal transduction; IGI:SGD. 
Interpro
 IPR006828; AMP_prot_kin_bsu_interact-dom. 
Pfam
 PF04739; AMPKBI 
SMART
 SM01010; AMPKBI 
PROSITE
  
PRINTS