CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019394
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger FYVE domain-containing protein 19 
Protein Synonyms/Alias
 MLL partner containing FYVE domain 
Gene Name
 ZFYVE19 
Gene Synonyms/Alias
 MPFYVE 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
331ERILALAKRLAMLRGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 ZN_FING 74 133 FYVE-type.
 MOD_RES 243 243 Phosphothreonine.
 MOD_RES 354 354 Phosphoserine.
 MOD_RES 463 463 Phosphoserine.  
Keyword
 Alternative splicing; Chromosomal rearrangement; Coiled coil; Complete proteome; Metal-binding; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 471 AA 
Protein Sequence
MNYDSQQPPL PPLPYAGCRR ASGFPALGRG GTVPVGVWGG AGQGREGRSW GEGPRGPGLG 60
RRDLSSADPA VLGATMESRC YGCAVKFTLF KKEYGCKNCG RAFCSGCLSF SAAVPRTGNT 120
QQKVCKQCHE VLTRGSSANA SKWSPPQNYK KRVAALEAKQ KPSTSQSQGL TRQDQMIAER 180
LARLRQENKP KLVPSQAEIE ARLAALKDER QGSIPSTQEM EARLAALQGR VLPSQTPQPA 240
HHTPDTRTQA QQTQDLLTQL AAEVAIDESW KGGGPAASLQ NDLNQGGPGS TNSKRQANWS 300
LEEEKSRLLA EAALELREEN TRQERILALA KRLAMLRGQD PERVTLQDYR LPDSDDDEDE 360
ETAIQRVLQQ LTEEASLDEA SGFNIPAEQA SRPWTQPRGA EPEAQDVDPR PEAEEEELPW 420
CCICNEDATL RCAGCDGDLF CARCFREGHD AFELKEHQTS AYSPPRAGQE H 471 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR000306; Znf_FYVE.
 IPR017455; Znf_FYVE-rel.
 IPR011011; Znf_FYVE_PHD.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF01363; FYVE 
SMART
 SM00064; FYVE
 SM00184; RING 
PROSITE
 PS50178; ZF_FYVE 
PRINTS