CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034388
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG142264, isoform CRA_a 
Protein Synonyms/Alias
 Protein Akr1b10 
Gene Name
 Akr1b10 
Gene Synonyms/Alias
 mCG_142264 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
145QIERLLNKPGLKHKPacetylation[1]
145QIERLLNKPGLKHKPsuccinylation[1]
145QIERLLNKPGLKHKPubiquitination[2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 288 AA 
Protein Sequence
MAAFVTLLTG AKMPIVGLGT WKNESEVGEA IQEKIQEKAV KREDLFIVSK LWSTFFEKSL 60
VKKAFQNTLS DLKLDYLDLY LIHWPQGFQS GNVFLPTDDK GSILSSKYTF LDAWEAMEEL 120
VDQGLVKALG VSNFNHFQIE RLLNKPGLKH KPVTNQVECH PYLTQEKLIQ YCHSKGITIT 180
AYSPLGSPDR PSAKPEDPLL LEIPKIKEIA AKHKRTAAQV LIRFHIERNV VVIPKSVTPS 240
RIQENIQVFD FQLSEEDMAA ILSFNRNWRA CGLFAASHNE DFPFHAEY 288 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00062; ALDOKETO_REDUCTASE_2
 PS00063; ALDOKETO_REDUCTASE_3 
PRINTS
 PR00069; ALDKETRDTASE.