CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026072
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Legumain 
Protein Synonyms/Alias
 Legumain, isoform CRA_a 
Gene Name
 Lgmn 
Gene Synonyms/Alias
 rCG_20691 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
179IRYMYEHKMYQKMVFacetylation[1]
281NKSISTMKVMQFQGMacetylation[1]
289VMQFQGMKHRASSPIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 435 AA 
Protein Sequence
MIWKVAVLLS LVLGAGAVHI GVDDPEDGGK HWVVIVAGSN GWYNYRHQAD ACHAYQIIHR 60
NGIPDEQIIV MMYDDIANNE ENPTPGVVIN RPNGTDVYKG VPKDYTGEDV TPENFLAVLR 120
GDEEAVKGKG SGKVLKSGPR DHVFVYFTDH GATGILVFPN EDLHVKDLNK TIRYMYEHKM 180
YQKMVFYIEA CESGSMMNHL PDDIDVYATT AANPNESSYA CYYDEERSTY LGDWYSVNWM 240
EDSDVEDLTK ETLHKQYHLV KSHTNTSHVM QYGNKSISTM KVMQFQGMKH RASSPISLPP 300
VTHLDLTPSP DVPLTILKRK LLRTNNMKES QVLVGQIQHL LDARHIIEKS VQKIVSLLAG 360
FGETAQKHLS ERAMLTAHDC HQEAVTHFRT HCFNWHSVMY EHALRYLYVL ANLCEKPYPI 420
DRIKMAMDKV CLSHY 435 
Gene Ontology
 GO:0045177; C:apical part of cell; IEA:Compara.
 GO:0005770; C:late endosome; IEA:Compara.
 GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
 GO:0040015; P:negative regulation of multicellular organism growth; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:Compara.
 GO:0001101; P:response to acid; IEA:Compara. 
Interpro
 IPR001096; Peptidase_C13. 
Pfam
 PF01650; Peptidase_C13 
SMART
  
PROSITE
  
PRINTS
 PR00776; HEMOGLOBNASE.