CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041852
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integrin alpha 7 
Protein Synonyms/Alias
 Integrin alpha-7 
Gene Name
 Itga7 
Gene Synonyms/Alias
 mCG_18693 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1081VPQYHAVKIPREDRQubiquitination[1]
1094RQQFKEEKTGTIQRSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell adhesion; Complete proteome; Integrin; Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1136 AA 
Protein Sequence
MARIPRCDFL RPPGIYYLIT SLLAGLFLPP AIAFNLDVMG AIRKEGEPGS LFGFSVALHR 60
QLQPRPQSWL LVGAPQALAL PGQQANRTGG LFACPLSLEE TDCYRVDIDR GANVQKESKE 120
NQWLGVSVRS QGPGGKIVTC AHRYESRQRV DQALETRDVI GRCFVLSQDL AIRDELDGGE 180
WKFCEGRPQG HEQFGFCQQG TAATFSPDSH YLVFGAPGTY NWKGLLFVTN IDSSDPDQLV 240
YKTLDPADRL TGPAGDLTLN SYLGFSIDSG KGLMRSEELS FVAGAPRANH KGAVVILRKD 300
SASRLIPEVV LSGERLTSGF GYSLAVTDLN NDGWADLIVG APYFFERQEE LGGAVYVYMN 360
QGGHWADISP LRICGSPDSM FGISLAVLGD LNQDGFPDIA VGAPFDGDGK VFIYHGSSLG 420
VVVKPSQVLE GEAVGIKSFG YSLSGGLDVD GNHYPDLLVG SLADTAALFR ARPVLHVSQE 480
IFIDPRAIDL EQPNCADGRL VCVDIKICFS YVAVPSSYSP SVALDYMLDG DTDRRLRGQV 540
PRVTFLSRGL DDLRHQSSGT VWLKHQHDRV CGDTVFQLQE NVKDKLRAIV VTLSYGLRTP 600
PLGRQAPGQE LPTVAPILNA HQPSTQRTEI HFLKQGCGED KICQSNLQLE RYQFCSRISD 660
TEFQALPMDL DGRTALFALS GQPFIGLELT VTNLPSDPAR PQADGDDAHE AQLLVTLPAS 720
LRYSGVRALD SVEKPLCLSN DSASHVECEL GNPMKRGAQV TFYLILSTSG ITIETTELEV 780
KLLLATISEQ ELDPVSVRAH VFIELPLSIS GVATPQQLFF SGEVKGESAM RSERDVGSKV 840
KYEVTVSNQG QSLNTLGSAF LNIMWPHEIA NGKWLLYPMR VELEGGQGPG KRGICSPRPN 900
ILQLDVDSRD RRRRELGQPE PQEPPEKVEP STSWWPVSSA EKRNVTLDCA QGTAKCVVFS 960
CPLYSFDRAA VLHVWGRLWN STFLEEYMAV KSLEVIVRAN ITVKSSIKNL LLRDASTVIP 1020
VMVYLDPMAV VVEGVPWWVI LLAVLAGLLV LALLVLLLWK LGFFKRAKHP EATVPQYHAV 1080
KIPREDRQQF KEEKTGTIQR SNWGNSQWEG SDAHPILAAD WHPELGPDGH PVPATA 1136 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0008305; C:integrin complex; IEA:Compara.
 GO:0043236; F:laminin binding; IMP:MGI.
 GO:0048514; P:blood vessel morphogenesis; IMP:MGI.
 GO:0007155; P:cell adhesion; IMP:MGI.
 GO:0016477; P:cell migration; IMP:MGI.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
 GO:0007519; P:skeletal muscle tissue development; IEA:Compara. 
Interpro
 IPR013519; Int_alpha_beta-p.
 IPR000413; Integrin_alpha.
 IPR013649; Integrin_alpha-2.
 IPR018184; Integrin_alpha_C_CS. 
Pfam
 PF08441; Integrin_alpha2 
SMART
 SM00191; Int_alpha 
PROSITE
 PS51470; FG_GAP
 PS00242; INTEGRIN_ALPHA 
PRINTS
 PR01185; INTEGRINA.