CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025883
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA1348 protein 
Protein Synonyms/Alias
  
Gene Name
 Pdp2 
Gene Synonyms/Alias
 mKIAA1348 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
443LVVGHLSKVGRHKPDubiquitination[1]
469QSLLLQRKASGLHAAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Hydrolase; Magnesium; Metal-binding; Protein phosphatase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 539 AA 
Protein Sequence
PPATCFRMSS TVSYWIFNSA RNRIALLRGG RRLYSRAATS RNLLKWRPFS PALASSALKC 60
GSPPGGFALR KAYRHTSTEE EDFHLQLSPE QVSDLLRAGE SSHKVLDFNN GVPNSVLRFE 120
SNQLAANSPV EDRQGVATCV QTNGMMFGIF DGHGGHACAQ AVSERLFYYM AVSLMSHQTL 180
EQMEEATENM KPLLPILRWL KHPGDSIYKD VTSVHLDHLR VYWQELLDLH MEMGLSIEEA 240
LMYSFQRLDS DISLEIQAPL EDEVTRNLSL QVAFSGATAC MAHVNGVHLH VANAGDCRAI 300
LGVQEENGAW SCLPLTCDHN AWNEAELSRL KREHPESEDR TLIIDDRLLG VLMPCRAFGD 360
VQLKWSKELQ RNVLARGFDT EALNIYQFTP PHYYTPPYLT AKPEVTYHRL RRQDKFLVLA 420
SDGLWDMLGN EDVVRLVVGH LSKVGRHKPD LDQRPANLGL MQSLLLQRKA SGLHAADQNT 480
ATHLIRHAIG SNEYGEMEPE RLAAMLTLPE DVARMYRDDI TVMVVFFNSD SIDTYCKEG 539 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004741; F:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; IEA:Compara.
 GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:Compara. 
Interpro
 IPR001932; PP2C-like.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
 PF00481; PP2C 
SMART
 SM00331; PP2C_SIG
 SM00332; PP2Cc 
PROSITE
 PS01032; PP2C 
PRINTS