CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009941
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Homeobox protein Hox-D13 
Protein Synonyms/Alias
 Homeobox protein Hox-4.8 
Gene Name
 Hoxd13 
Gene Synonyms/Alias
 Hox-4.8 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
162LGGFPVEKYMDVSGLacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
 Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. 
Sequence Annotation
 DNA_BIND 272 331 Homeobox.  
Keyword
 Complete proteome; Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 339 AA 
Protein Sequence
MSRSGTWDMD GLRADGGAAG AAPASSSSSV AAPGQCRGFL SAPVFAGTHS GRAAAAAAAA 60
AAAAAAASSF AYPGTSERTG SSSSSSSSAV IATRPEAPVA KECPAPAAAA TAAAPPGAPA 120
LGYGYHFGNG YYSCRMSHGV GLQQNALKSS PHASLGGFPV EKYMDVSGLA SSSVPTNEVP 180
ARAKEVSFYQ GYTSPYQHVP GYIDMVSTFG SGEPRHEAYI SMEGYQSWTL ANGWNSQVYC 240
AKDQPQGSHF WKSSFPGDVA LNQPDMCVYR RGRKKRVPYT KLQLKELENE YAINKFINKD 300
KRRRISAATN LSERQVTIWF QNRRVKDKKI VSKLKDTVS 339 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.
 GO:0060602; P:branch elongation of an epithelium; IMP:MGI.
 GO:0042733; P:embryonic digit morphogenesis; IGI:MGI.
 GO:0048619; P:embryonic hindgut morphogenesis; IEA:Compara.
 GO:0030539; P:male genitalia development; IMP:MGI.
 GO:0060571; P:morphogenesis of an epithelial fold; IMP:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IGI:MGI.
 GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IMP:MGI.
 GO:0042127; P:regulation of cell proliferation; IMP:MGI.
 GO:0001501; P:skeletal system development; IMP:MGI.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR017970; Homeobox_CS.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR022067; HoxA13_N. 
Pfam
 PF00046; Homeobox
 PF12284; HoxA13_N 
SMART
 SM00389; HOX 
PROSITE
 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2 
PRINTS