CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025744
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG16699 
Protein Synonyms/Alias
  
Gene Name
 Cldn3 
Gene Synonyms/Alias
 mCG_16699 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
194RDKYAPTKILYSAPRubiquitination[1]
216TGTAYDRKDYV****ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell junction; Cell membrane; Membrane; Tight junction; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 219 AA 
Protein Sequence
MSMGLEITGT SLAVLGWLCT IVCCALPMWR VSAFIGSSII TAQITWEGLW MNCVVQSTGQ 60
MQCKMYDSLL ALPQDLQAAR ALIVVSILLA AFGLLVALVG AQCTNCVQDE TAKAKITIVA 120
GVLFLLAALL TLVPVSWSAN TIIRDFYNPL VPEAQKREMG AGLYVGWAAA ALQLLGGALL 180
CCSCPPRDKY APTKILYSAP RSTGPGTGTG TAYDRKDYV 219 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0005923; C:tight junction; IDA:MGI.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0001666; P:response to hypoxia; IEA:Compara. 
Interpro
 IPR006187; Claudin.
 IPR003549; Claudin3.
 IPR017974; Claudin_CS.
 IPR004031; PMP22/EMP/MP20/Claudin. 
Pfam
 PF00822; PMP22_Claudin 
SMART
  
PROSITE
 PS01346; CLAUDIN 
PRINTS
 PR01077; CLAUDIN.
 PR01378; CLAUDIN3.