CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015287
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 N-alpha-acetyltransferase 50 
Protein Synonyms/Alias
 N-acetyltransferase NAT13; NatE catalytic subunit 
Gene Name
 Naa50 
Gene Synonyms/Alias
 Mak3; Nat13 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
16DVTPHNIKQLKRLNQubiquitination[1]
33FPVSYNDKFYKDVLEubiquitination[1]
36SYNDKFYKDVLEVGEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity (By similarity). 
Sequence Annotation
 DOMAIN 6 155 N-acetyltransferase.
 REGION 79 90 Coenzyme A binding (By similarity).
 MOD_RES 12 12 Phosphothreonine (By similarity).
 MOD_RES 34 34 N6-acetyllysine (By similarity).
 MOD_RES 37 37 N6-acetyllysine (By similarity).
 MOD_RES 110 110 Phosphotyrosine (By similarity).  
Keyword
 Acetylation; Acyltransferase; Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 169 AA 
Protein Sequence
MKGRIELGDV TPHNIKQLKR LNQVIFPVSY NDKFYKDVLE VGELAKLAYF NDIAVGAVCC 60
RVDHSQNQKR LYIMTLGCLA PYRRLGIGTK MLNHVLNICE KDGTFDNIYL HVQISNESAI 120
DFYRKFGFEI IETKKNYYKR IEPADAHVLQ KNLKVPSGQN AETQKTDN 168 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:HGNC.
 GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
 GO:0006474; P:N-terminal protein amino acid acetylation; TAS:HGNC. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 
Pfam
 PF00583; Acetyltransf_1 
SMART
  
PROSITE
 PS51186; GNAT 
PRINTS