CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035040
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Rho-associated protein kinase 1 
Protein Synonyms/Alias
  
Gene Name
 Rock1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
151TSLQEEVKHLKHNLEacetylation[1]
230VAMCEMEKKLKEEREacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 980 AA 
Protein Sequence
MLLQHRINEY QRKVEQENEK RRNVENEVST LKDQLEDLRK ASQSSQLANE KLTQLQKQLE 60
EANDLLRTES DTAVRLRKSH TEMSKSVSQL ESLNRELQER NRMLENSKSQ ADKDYYQLQA 120
VLEAERRDRG HDSEMIGDLQ ARITSLQEEV KHLKHNLERV EGERKEAQDM LNHSEKEKNN 180
LEIDLNYKLK SIQQRLEQEV NEHKVTKARL TDKHQSIEEA KSVAMCEMEK KLKEEREARE 240
KAENRVVETE KQCSMLDVDL KQSQQKLEHL TENKERLEDA VKSLTLQLEQ ESNKRILLQS 300
ELKTQAFEAD NLKGLEKQMK QEINTLLEAK RLLEFELAQL TKQYRGNEGQ MRELQDQLEA 360
EQYFSTLYKT QVKELKEEIE EKNRENLRKI QELQSEKETL STQLDLAETK AESEQLARGI 420
LEEQYFELTQ ESKKAASRNR QEITDKDHTV SRLEEANNAL TKDIELLRKE NEELNERMRT 480
AEEEYKLKKE EEISNLKAAF EKNISTERTL KTQAVNKLAE IMNRKDFKID RKKANTQDLR 540
KKEKENRKLQ LELNQEREKF NQMVVKHQKE LNDMQAQLVE ECTHRNELQM QLASKESDIE 600
QLRAKLLDLS DSTSVASFPS ADETDGNLPV GSACIPYLFI FYSSESRIEG WLSVPNRGNI 660
KRYGWKKQYV VVSSKKMLFY NDEQDKEQSS PSMVLDIDKL FHVRPVTQGD VYRAETEEIP 720
KIFQILYANE GECRKDIEVE PVQQGEKTNF QNHKGHEFIP TLYHFPANCE ACAKPLWHVF 780
KPPPALECRR CHVKCHRDHL DKKEDLISPC KVSYDVTSAR DMLLLACSQD EQKKWVTHLV 840
KKIPKNPPSG FVRASPRTLS TRSTANQSFR KVVKNTSGKT RLMPSSPCRV GVGIDKWRSH 900
RDRKREGLLT EDVPGSRLEK KLGRIGRAAR RNKDGADIQP CLDINDLLCM CRLVPLLGLP 960
LVVTSGTAHV QFMHQVLVDR 980 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd.
 IPR020684; Rho-assoc_coiled-coil_kin.
 IPR015008; Rho-bd_dom. 
Pfam
 PF00169; PH
 PF08912; Rho_Binding 
SMART
 SM00109; C1
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN
 PS50081; ZF_DAG_PE_2 
PRINTS