CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013489
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 93 
Protein Synonyms/Alias
  
Gene Name
 CCDC93 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
45GYFRARIKGLSPFDKubiquitination[1]
89QKIALSEKIVSVLPRubiquitination[1]
131VKRAIETKEEMGDYIubiquitination[1]
148YSVSQFQKTYSLPEDubiquitination[1, 2]
160PEDDDFIKRKEKAIKubiquitination[2]
177VDLSEVYKPRRKYKRubiquitination[1]
259RIQSLMTKMTAMANEubiquitination[1]
287GLCSAEIKQIVSEYAubiquitination[1]
351QARYNEAKKTLTELKacetylation[3]
352ARYNEAKKTLTELKTacetylation[3]
363ELKTYSEKLDKEQAAubiquitination[1]
377ALEKIESKADPSILQubiquitination[1, 2]
397VAMNENLKSQEQEFKubiquitination[1, 2]
404KSQEQEFKAHCREEMubiquitination[1]
422QQEIENLKAERAPRGubiquitination[1]
499AELIQYQKRFIELYRubiquitination[1]
571EQIVEGIKQSRMKMEubiquitination[1]
601QYLELLEKQRLYFKTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
  
Sequence Annotation
 MOD_RES 298 298 Phosphoserine.
 MOD_RES 301 301 Phosphoserine.
 MOD_RES 305 305 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 631 AA 
Protein Sequence
MGLPRGPEGQ GLPEVETRED EEQNVKLTEI LELLVAAGYF RARIKGLSPF DKVVGGMTWC 60
ITTCNFDVDV DLLFQENSTI GQKIALSEKI VSVLPRMKCP HQLEPHQIQG MDFIHIFPVV 120
QWLVKRAIET KEEMGDYIRS YSVSQFQKTY SLPEDDDFIK RKEKAIKTVV DLSEVYKPRR 180
KYKRHQGAEE LLDEESRIHA TLLEYGRRYG FSRQSKMEKA EDKKTALPAG LSATEKADAH 240
EEDELRAAEE QRIQSLMTKM TAMANEESRL TASSVGQIVG LCSAEIKQIV SEYAEKQSEL 300
SAEESPEKLG TSQLHRRKVI SLNKQIAQKT KHLEELRASH TSLQARYNEA KKTLTELKTY 360
SEKLDKEQAA LEKIESKADP SILQNLRALV AMNENLKSQE QEFKAHCREE MTRLQQEIEN 420
LKAERAPRGD EKTLSSGEPP GTLTSAMTHD EDLDRRYNME KEKLYKIRLL QARRNREIAI 480
LHRKIDEVPS RAELIQYQKR FIELYRQISA VHKETKQFFT LYNTLDDKKV YLEKEISLLN 540
SIHENFSQAM ASPAARDQFL RQMEQIVEGI KQSRMKMEKK KQENKMRRDQ LNDQYLELLE 600
KQRLYFKTVK EFKEEGRKNE MLLSKVKAKA S 631 
Gene Ontology
  
Interpro
 IPR019159; DUF2037. 
Pfam
 PF09762; KOG2701 
SMART
  
PROSITE
  
PRINTS