CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035361
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Matrix metalloproteinase 21 (Predicted) 
Protein Synonyms/Alias
 Protein Mmp21 
Gene Name
 Mmp21 
Gene Synonyms/Alias
 Mmp21_predicted; rCG_47420 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
89QAVRRFQKANRLPASacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 283 283 By similarity.  
Keyword
 Calcium; Complete proteome; Disulfide bond; Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 568 AA 
Protein Sequence
MLAVSDLRLT MLLCWLVTPQ PAQPERLFHS RDRSDLEPSP LSRAKPIADL HAAQNFLLKY 60
GWSEVSSPKE SAGVPVGFTL AQAVRRFQKA NRLPASGKLD SPTLAAMNKP RCGVPDTRLP 120
LQDALPTPPA LPTPLGLQPR ARQKRFLQML LPKPGGKQEG RSDTGASRVF SKKTLTWRLV 180
GDAYSSQLSG DEQRYIFRLA FRMWSEVTPL DFREDLTAPG TMVDIKLGFG RGRHLGCPRV 240
FDGSGQEFAH AWHLGEIHFD DDEHFTPLSS DTGISLLKVA VHEIGHVLGL PHTYRVGSIM 300
QPNYIPQEPA FELDWSDRKA IQRLYGSCEG SFDIVFDWIR KERNQYGEVR VRFNTYFFRN 360
SWYWLYENRN NRTRYGDPLQ ILTGWRGIPM QRIDAFVHVW SWGRDERYFF KGNQYWRYDS 420
ENDQAHTQDE QGRSYPKLIS EGFPGIPSPL DTAFYERRQQ LIYFFKESLV YAFDVNRNQA 480
LSSYPKKMSQ VFPAIMPQNH PFRNLDSAYY SYAHNAIFFF KGNSFWKVVS DKDKQQDSRL 540
PLNGLFPKQS VSGKWFDVCD VHTSTLNM 568 
Gene Ontology
 GO:0031012; C:extracellular matrix; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR000585; Hemopexin-like_dom.
 IPR018487; Hemopexin-like_repeat.
 IPR024079; MetalloPept_cat_dom.
 IPR001818; Pept_M10_metallopeptidase.
 IPR021190; Pept_M10A.
 IPR016293; Pept_M10A_Metazoans.
 IPR006026; Peptidase_Metallo.
 IPR002477; Peptidoglycan-bd-like. 
Pfam
 PF00045; Hemopexin
 PF00413; Peptidase_M10
 PF01471; PG_binding_1 
SMART
 SM00120; HX
 SM00235; ZnMc 
PROSITE
  
PRINTS
 PR00138; MATRIXIN.