UniProt Accession

 B8ZZ67_HUMAN; B8ZZ67 

Genbank Protein ID

 AC079354; CH471063 

Genbank Nucleotide ID

 EAW70306.1 

Protein Name

 SMT3 suppressor of mif two 3 homolog 1 (Yeast), isoform CRA_b 

Protein Synonyms/Alias

 Small ubiquitin-related modifier 1 

Gene Name

 SUMO1 

Gene Synonyms/Alias

 hCG_1776791 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
7	*MTTHLKKLKESYCQ	ubiquitination	[1, 2]
9	TTHLKKLKESYCQRQ	ubiquitination	[1, 2, 3, 4]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 62 AA 

Protein Sequence

Gene Ontology

 GO:0030425; C:dendrite; IEA:Compara.
 GO:0016604; C:nuclear body; IEA:Compara.
 GO:0045202; C:synapse; IEA:Compara.
 GO:0019789; F:SUMO ligase activity; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0030578; P:PML body organization; IEA:Compara.
 GO:0090204; P:protein localization to nuclear pore; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:Compara. 

Interpro

 IPR022617; SUMO.
 IPR019955; Ubiquitin_supergroup. 

Pfam

 PF11976; Rad60-SLD 

SMART

  

PROSITE

 PS50053; UBIQUITIN_2 

PRINTS