CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012405
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein FAM83H 
Protein Synonyms/Alias
  
Gene Name
 Fam83h 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
222TYYCRTGKSFKGHLKacetylation[1]
225CRTGKSFKGHLKEKFacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 May play a major role in the structural organization and calcification of developing enamel (By similarity). 
Sequence Annotation
 MOD_RES 515 515 Phosphoserine.
 MOD_RES 522 522 Phosphoserine.
 MOD_RES 639 639 Phosphoserine (By similarity).
 MOD_RES 752 752 Phosphoserine (By similarity).
 MOD_RES 778 778 Phosphoserine (By similarity).
 MOD_RES 841 841 Phosphoserine.
 MOD_RES 871 871 Phosphoserine (By similarity).
 MOD_RES 873 873 Phosphothreonine (By similarity).
 MOD_RES 893 893 Phosphoserine.
 MOD_RES 904 904 Phosphoserine.
 MOD_RES 926 926 Phosphoserine.
 MOD_RES 937 937 Phosphoserine (By similarity).
 MOD_RES 948 948 Phosphoserine.
 MOD_RES 959 959 Phosphoserine.
 MOD_RES 970 970 Phosphoserine.
 MOD_RES 977 977 Phosphoserine (By similarity).
 MOD_RES 1035 1035 Phosphoserine (By similarity).
 MOD_RES 1041 1041 Phosphoserine.
 MOD_RES 1057 1057 Phosphoserine (By similarity).
 MOD_RES 1072 1072 Phosphothreonine (By similarity).
 MOD_RES 1080 1080 Phosphoserine (By similarity).  
Keyword
 Biomineralization; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1209 AA 
Protein Sequence
MARRSQSSSQ GDNPLAPGYL PPHYKEYYRL AVDALTEGGP EAYNRFLASE GAPDFLCPEE 60
LEHVSRHLQP PQYVAREPPE GTPSDVDMDG SSGTYWPVNS DQAVPELDLG WPLTFGFQGT 120
EVTTLVQPPP PDSPSIKDEA RRMIRSAQQV VAVVMDMFTD VDLLSEVLEA AARRVPVYIL 180
LDEMNAQHFL DMADKCRVNL HHVDFLRVRT VAGPTYYCRT GKSFKGHLKE KFLLVDCAVV 240
MSGSYSFMWS FEKIHRSLAH VFQGELVSSF DEEFRILFAQ SEPLVPSAGA LARMDAYALA 300
PYSGAGPLVG VPGVGAPTPF SFPKRAHLLF PPPREEGLGF PSFLDPDRHF LSAFRREELQ 360
RMPGGALEPH TGLRPLARPT EAGPFGELAG PRGFFQSRHL EMDAFKRHSY ATPDGAGAVE 420
NFAAARQVSR QTFLSHGDDF RFQTSHFQRD QLYQQHYQWD PQFAPARPQG LFEKLRAGRP 480
GFADPDDFAL GAGHRFPELG ADVHQRLEYV PSSASREVRH GSDPAFGPSP RGLEPSGASR 540
PNLGQRFPCQ ATLRQGLDTA SEAEPERRGG PEGRAGLRHW RLASYLSGCH GDGGEEGLPM 600
EAEACEDEVL APGGRDLLPS AFRTPAAFPA KGPKPGSGSG GGDSSEREGP EETSLAKQDS 660
FRSRLNPLIQ RSSRLRSSLI FASQAEGAVG TAAATTEKVQ LMHKEQTVSE TLGPSGEAVR 720
SSASAKVAEL LEKYKGPARD PGGAGGAVTS SSHSKAVVSQ AWREEVVAPG GAGTERRSLE 780
SCLLDLRDSF AQQLHQEAER HPGAASLTAA QLLDTLGGTD RLPSRFLSAQ GRSLSPQGRD 840
SPPPEGLGTH QLPYSEPKGN PTPAYPERKG SPTPAYPERK GSPTPAYPER KGSPTPAYPE 900
RKGSPTQAYP ERKGSPTSGF PNRRGSPTTG LMEQKGSPTS TYPDRRGSPV PPVPERRGSP 960
VPPVPERRGS LTFAGESSKT GPTEEVSSGP MEVLRKGSLR LRQLLSPKNE RRGEDEGSFP 1020
TPQENGQPES PRRPSLSRGD STEAAAEERG SRVRLASATA NALYSSNLRD DTKAILEQIS 1080
AHGQKHRGVP APGPAHSSPD VGRPTTAGDL APDMSDKDKC SAIFRSDSLG TQGRLSRTLP 1140
GSAEERDRLL RRMESMRKEK RVYSRFEVFC KKDEAGSSGA GDNLADEDTR DSKMGKFVPK 1200
ILGTFKSKK 1209 
Gene Ontology
 GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW. 
Interpro
 IPR012461; DUF1669. 
Pfam
 PF07894; DUF1669 
SMART
  
PROSITE
  
PRINTS