CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043991
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase RNF8 
Protein Synonyms/Alias
  
Gene Name
 RNF8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
74TQKGNSKKVVQMEQEubiquitination[1]
124LEIAQGEKDLKQQLAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 208 AA 
Protein Sequence
XPSKTTGAPI YPGFPKVTEV HHEQKASNSS ASQRSLQMFK VTMSRILRLK IQMQEKHEAV 60
MNVKKQTQKG NSKKVVQMEQ ELQDLQSQLC AEQAQQQARV EQLEKTFQEE EQHLQGLEIA 120
QGEKDLKQQL AQALQEEEKE KMQAQKEEVL SHMNDVLENE LQCIICSEYF IEQRDCSEDR 180
ALRAFERLPG SASLRWSGGF SLAVTPLL 208 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
 GO:0051301; P:cell division; IEA:InterPro.
 GO:0016567; P:protein ubiquitination; IEA:InterPro.
 GO:0006974; P:response to DNA damage stimulus; IEA:InterPro. 
Interpro
 IPR017335; E3_Ub_ligase_RNF8. 
Pfam
  
SMART
  
PROSITE
  
PRINTS