UniProt Accession

 E5RGH2_HUMAN; E5RGH2 

Genbank Protein ID

 AC091050 

Genbank Nucleotide ID

  

Protein Name

 CCR4-NOT transcription complex subunit 7 

Protein Synonyms/Alias

  

Gene Name

 CNOT7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	KIRQVIRKYNYVAMD	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 147 AA 

Protein Sequence

Gene Ontology

 GO:0030014; C:CCR4-NOT complex; IEA:Compara.
 GO:0000932; C:cytoplasmic mRNA processing body; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:Compara.
 GO:0033962; P:cytoplasmic mRNA processing body assembly; IEA:Compara.
 GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:Compara.
 GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara. 

Interpro

 IPR006941; RNase_CAF1.
 IPR012337; RNaseH-like_dom. 

Pfam

 PF04857; CAF1 

SMART

  

PROSITE

  

PRINTS