CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009357
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DEP domain-containing protein 5 
Protein Synonyms/Alias
  
Gene Name
 Depdc5 
Gene Synonyms/Alias
 Kiaa0645 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1562KFADRLLKDFTDFCIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 1175 1250 DEP.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1591 AA 
Protein Sequence
MRTTKVYKLV IHKKGFGGSD DELVVNPKVF PHIKLGDIVE IAHPNDEYSP LLLQVKSLKE 60
DLQKETISVD QTVTQVFRLR PYQDVYVNVV DPKDVTLDLV ELTFKDQYIG RGDMWRLKKS 120
LVSTCAYITQ KVEFAGIRAQ AGELWVKNEK VMCGYISEET RVVFRSTSAM VYIFIQMSCE 180
MWDFDIYGDL YFEKAVNGFL ADLFTKWKEK NCSHEVTVVL FSRTFYDAKS IDEFPEINRA 240
SIQEDHKGRF YEDFYKVVVQ NERREEWTSL LVTIKKLFIQ YPVLVRLEQA GGFPQGDNST 300
SAQGNYLEAI NLSFNVFDKH YINRNFDRTG QMSVVITPGV GVFEVDRLLM ILTKQRMIDN 360
GIGVDLVCMG EQPLHAVPLF KLHNRSVPRD SRLGDDYNIP HWINHSFYTS KSQLFCNSFT 420
PRIKLAGKKS ASEKTKNGRD TSLGTPKESE NTLPIQVDYD AYDAQVFRLP GPSRAQRLAT 480
CRSVREQENH SRKSASSCDV SSSPSLPSRA LPTEEVRSQA SDDSSLGKST NILMIPNPHL 540
HQYEVSSSLG YTSTRDVLEN MIEPPQRDSS APGRFHVGSA ESMLHVRPGG YTPQRALINP 600
FAPSRMPMKL TSNRRRWMHT FPVGPSGEAI QIHHQTRQNM AELQGSRQRD PTHSSAELLE 660
LAYHEAAGRH STSRQPGDSM SLNFSGTEEL SVSLLSNSST GVNPRTQNKD SLEDSVSTSP 720
DPMPGFCCTV GVDWKSLTTP ACLPLTTDYF PDRQGLQNDY TEGCYDLLPE ADMDRRDEEG 780
VQMTAQQVFE EFICQRLMQG YQIIVQPKTQ KPNTTVPPPL SSSPLYSRGL VSRNRPEEEG 840
QYWLSMGRTF HKVTLKDKMI TVTRYLPKYP YESAQIHYTY SLCPSHSDSE FVSCWVDFCH 900
ERLEEYKWNY LDQYICSAGS EDFSLIESLK FWRTRFLLLP ACVTATKRIT EGEVHCDIYG 960
DKPRADEDEW QLLDGFIRFV EGLNRIRRRH RSDRMIRKGT AMKGLQMTGP ISAHSLEAAG 1020
PPVGKKGTSA LSALLEMEAS QKSLGEQQTT VHGKSSTQPA ENSSVAMTPT YVDSPRKDGA 1080
FFMEFVRSPR TASSAFYPQA SVDQTAPLVL DSTSLGVSTG QPMDRGNNQT FGNSQNIEQA 1140
FPSANSGDYS SQQHVASSLT SSSTLVEILE AMKHPSTGVQ LLSEQKGLSP CCFISAEVVH 1200
WLMNNVEGVQ TQAMGIDIMQ KMLEEQLITH ASGEAWRTFI YGFYFYKIVM DKEPERVAMQ 1260
QPSAPWYTAG ADDFASFQRK WFEVAFVAEE LVHSEIPAFL LPWLPSRPAS YASRHSSFSR 1320
SFGGRSQAAA LLAATVPEQR TVTLDVDVNN RTDRLEWCSC YYHGNFSLNA AFEIKLHWMA 1380
VTATVLFEMV QGWHRKATSC GFLLVPVLEG PFALPSYLYG DPLRAQLFIP LNLSCLLKEG 1440
SEHLFDSFEP ETYWDRMHLF QEAIAHRFGF VQDKYSVSAF NFPAENKPQY IHVTGTVFLQ 1500
LPYSKRKFSG QQRRRRNSTS STNQNMFCEE RVGYNWAYNT MLTKTWRSSA TGDEKFADRL 1560
LKDFTDFCIN RDNRLVTFWT NCLEKMHASA P 1591 
Gene Ontology
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR000591; DEP_dom.
 IPR027244; IML1.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00610; DEP
 PF12257; DUF3608 
SMART
 SM00049; DEP 
PROSITE
 PS50186; DEP 
PRINTS