CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034813
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Akr1cl 
Protein Synonyms/Alias
 RCG55789, isoform CRA_b 
Gene Name
 Akr1cl 
Gene Synonyms/Alias
 rCG_55789 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
4****MDLKHSRSVKLacetylation[1]
10LKHSRSVKLNDGNLMacetylation[1]
28GFGTFASKEIPKSKAacetylation[1]
247PVLMTIAKKHNQTPGacetylation[1]
271RGVVVLAKSFNEKRIacetylation[1]
276LAKSFNEKRIKENFQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 56 56 Proton donor (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 324 AA 
Protein Sequence
MDLKHSRSVK LNDGNLMPVL GFGTFASKEI PKSKAAEATK VAIDVGFRHI DAAYFYQNEE 60
EVGQALRDKM ADGTVKREDL FYTTKIWITF LRPELVRQCL ERSLKKLGLD YVDLCIIHIP 120
IAMKPGEELL PKDANGKFIF DTVDIRDTWE ALEKCKDAGL SKSIGVSNFN HKQLELILNK 180
PRLKYKPTCN QVECHPYLNQ SKLLEFCKSK DIVLVAYSAL GSHRDSSWVS SDSPYLLEDP 240
VLMTIAKKHN QTPGQVALRY QLQRGVVVLA KSFNEKRIKE NFQVFDFELT PEDMKTIDSL 300
NRNFRYSQMA FALDHPDYPF LEEY 324 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2
 PS00063; ALDOKETO_REDUCTASE_3 
PRINTS
 PR00069; ALDKETRDTASE.