UniProt Accession

 PECR_MOUSE; Q99MZ7; Q9CX01; Q9JIF4 

Genbank Protein ID

 AF232011; AF242204; AK010260; BC013530 

Genbank Nucleotide ID

 AAF69800.1; AAK28336.1; BAB26803.1; AAH13530.1 

Protein Name

 Peroxisomal trans-2-enoyl-CoA reductase 

Protein Synonyms/Alias

 TERP 

Gene Name

 Pecr 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
32	GGGTGIGKAVSRELL	ubiquitination	[1]
92	EEVSNLVKSTLAKYG	acetylation	[2]
97	LVKSTLAKYGKINFL	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity (By similarity). 

Sequence Annotation

 NP_BIND 23 47 NADP (By similarity).
 MOTIF 301 303 Microbody targeting signal (By
 ACT_SITE 179 179 Proton acceptor (By similarity).  

Keyword

 Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; NADP; Oxidoreductase; Peroxisome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 303 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:UniProtKB.
 GO:0005778; C:peroxisomal membrane; ISS:UniProtKB.
 GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; ISS:UniProtKB.
 GO:0030497; P:fatty acid elongation; ISA:MGI.
 GO:0033306; P:phytol metabolic process; IEA:Compara. 

Interpro

 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom. 

Pfam

  

SMART

  

PROSITE

 PS00061; ADH_SHORT 

PRINTS

 PR00081; GDHRDH.