CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027488
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG3508, isoform B 
Protein Synonyms/Alias
  
Gene Name
 Hexim 
Gene Synonyms/Alias
 CG3508; Dmel_CG3508 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
186SKAQNISKEFGAKLRacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 360 AA 
Protein Sequence
MAEAVKNGKN RHSGSAEKES GSQQRPLDSG GGGGASGGGG VAVGGGSGMP KRKHRRGKKS 60
KMQPKKTKNH YPQWKLDMST GAGATLEGNQ RQNSRTKLVR SRSLLVPYNT NRFLMEEHMS 120
ELHKDDSDDN CFGSQTEDQV LFLSKEFSDV YERARLERLE TMSKQELIQE CMQIEDRYSK 180
AQNISKEFGA KLRAQDDKIR QLSRENQFLR THLLRTCSAT AGPAAAAAAA ASPPSAVAPT 240
PSSACELQAR QQPPQQPQPT PMDSTSEDSE SDSSSTTSST TSTTSSTSSD GHEMGVAGLN 300
IANGHAERHE RSRTRSRSRS PIHLNGHANE EERQRLLDGN QMEEDDNSSD VSRPADAVVK 360 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0097322; F:7SK snRNA binding; IDA:FlyBase.
 GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:InterPro.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:InterPro. 
Interpro
 IPR024872; HEXIM. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR02094; HEXIMFAMILY.