UniProt Accession

 HPCA_HUMAN; P84074; B2R9T3; D3DPQ7; P32076; P41211; P70510 

Genbank Protein ID

 D16593; AB015202; AK313907; CH471059; CH471059; CH471059; BC001777 

Genbank Nucleotide ID

 BAA04019.1; BAA74456.1; BAG36630.1; EAX07495.1; EAX07496.1; EAX07498.1; AAH01777.1 

Protein Name

 Neuron-specific calcium-binding protein hippocalcin 

Protein Synonyms/Alias

 Calcium-binding protein BDR-2 

Gene Name

 HPCA 

Gene Synonyms/Alias

 BDR2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
137	KMVSSVMKMPEDEST	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds two calcium ions. 

Sequence Annotation

 DOMAIN 24 59 EF-hand 1.
 DOMAIN 60 95 EF-hand 2.
 DOMAIN 96 131 EF-hand 3.
 DOMAIN 144 179 EF-hand 4.
 LIPID 2 2 N-myristoyl glycine (By similarity).  

Keyword

 Calcium; Complete proteome; Lipoprotein; Metal-binding; Myristate; Polymorphism; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 193 AA 

Protein Sequence

Gene Ontology

 GO:0003779; F:actin binding; IDA:UniProtKB.
 GO:0005509; F:calcium ion binding; NAS:UniProtKB.
 GO:0048839; P:inner ear development; IEA:Compara. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001125; Recoverin. 

Pfam

 PF00036; efhand 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS

 PR00450; RECOVERIN.