CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041233
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin conjugation factor E4 B 
Protein Synonyms/Alias
  
Gene Name
 Ube4b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
426LGELCETKFGKTHPMacetylation[1]
481DDAKVVEKYFSGPAIubiquitination[2]
665NRTVEDLKNNESQWKubiquitination[2]
672KNNESQWKDSPLATRubiquitination[2]
929VQEEMKNKEQWDQLPubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 998 AA 
Protein Sequence
MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASAPGPS QSLGLNVHNM 60
TPATSPIGAA GVAHRSQSSE GVSSLSSSPS NSLETQSQSL SRSQSMDIDG VSCEKSMSQV 120
DVDSGIENME VDENDRREKR SLSDKEPSSG PEVSEEQALQ LVCKIFRVSW KDRDRDVIFL 180
SSLSAQFKQN PKEVFSDFKD LIGQILMEVL MMSTQTRDEN PFASLTATSQ PIATAARSPD 240
RNLMLNTGSS SGTSPMFCNM GSFSTSSLSS LGASGGASNW DSYSDHFTIE TCKETDMLNY 300
LIECFDRVGI EEKKAPKMCS QPAVSQLLSN IRSQCISHTA LVLQGSLTQP RSLQQPSFLV 360
PYMLCRNLPY GFIQELVRTT HQDEEVFKQI FIPILQGLAL AAKECSLESD YFKYPLMALG 420
ELCETKFGKT HPMCNLVASL PLWLPKSLSP GSGRELQRLS YLGAFFSFSV FAEDDAKVVE 480
KYFSGPAITL ENTRVVSQSL QHYLELGRQE LFKILHSILL NGETREAALS YMAALVNANM 540
KKAQMQADDR LVSTDGFMLN LLWVLQQLST KIKLETVDPT YIFHPRCRIT LPNDETRINA 600
TMEDVNERLT ELYGDQPPFS EPKFPTECFF LTLHAHHLSI LPSCRRYIRR LRAIRELNRT 660
VEDLKNNESQ WKDSPLATRH REMLKRCKTQ LKKLVRCKAC ADAGLLDESF LRRCLNFYGL 720
LIQLMLRILD PAYPDVTLPL NSEVPKVFAA LPEFYVEDVA EFLFFIVQYS PQVLYEPCTQ 780
DIVMFLVVML CNQNYIRNPY LVAKLVEVMF MTNPSVQPRT QKFFEMIENH PLSTKLLVPS 840
LMKFYTDVEH TGATSEFYDK FTIRYHISTI FKSLWQNIAH HGTFMEEFNS GKQFVRYINM 900
LINDTTFLLD ESLESLKRIH EVQEEMKNKE QWDQLPRDQQ QARQSQLAQD ERVSRSYLAL 960
ATETVDMFHL LTKQVQKPFL RPLGPSCCPS FPRSLVPD 998 
Gene Ontology
 GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
 GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR019474; Ub_conjug_fac_E4_core. 
Pfam
 PF10408; Ufd2P_core 
SMART
  
PROSITE
  
PRINTS