CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008544
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 39S ribosomal protein L12, mitochondrial 
Protein Synonyms/Alias
 L12mt; MRP-L12; 5c5-2 
Gene Name
 MRPL12 
Gene Synonyms/Alias
 RPML12 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
150VKLIKEIKNYIQGINubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Mitochondrion; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG APLDNAPKEY 60
PPKIQQLVQD IASLTLLEIS DLNELLKKTL KIQDVGLVPM GGVMSGAVPA AAAQEAVEED 120
IPIAKERTHF TVRLTEAKPV DKVKLIKEIK NYIQGINLVQ AKKLVESLPQ EIKANVAKAE 180
AEKIKAALEA VGGTVVLE 198 
Gene Ontology
 GO:0005762; C:mitochondrial large ribosomal subunit; IDA:UniProtKB.
 GO:0003723; F:RNA binding; TAS:ProtInc.
 GO:0003735; F:structural constituent of ribosome; TAS:ProtInc.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:HGNC.
 GO:0006390; P:transcription from mitochondrial promoter; IDA:HGNC.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR015607; Ribosomal_L12_mit.
 IPR014719; Ribosomal_L7/12_C/ClpS-like.
 IPR013823; Ribosomal_L7/L12_C.
 IPR008932; Ribosomal_L7/L12_oligo. 
Pfam
 PF00542; Ribosomal_L12 
SMART
  
PROSITE
  
PRINTS