CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044409
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Peptidyl-prolyl cis-trans isomerase FKBP8 
Protein Synonyms/Alias
  
Gene Name
 FKBP8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
278NSYDLAIKAITSSAKubiquitination[1, 2, 3]
300EAQLLQLKVKCLNNLubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 441 AA 
Protein Sequence
MGVGAGRVSQ SGAPSPGGAG RANSCPPSSM ASCAEPSEPS APLPAGVPPL EDFEVLDGVE 60
DAEGEEEEEE EEEEEDDLSE LPPLEDMGQP PAEEAEQPGA LAREFLAAME PEPAPAPAPE 120
EWLDILGNGL LRKKTLVPGP PGSSRPVKGQ VVTVHLQTSL ENGTRVQEEP ELVFTLGDCD 180
VIQALDLSVP LMDVGETAMV TADSKYCYGP QGRSPYIPPH AALCLEVTLK TAVDGPDLEM 240
LTGQERVALA NRKRECGNAH YQRADFVLAA NSYDLAIKAI TSSAKVDMTF EEEAQLLQLK 300
VKCLNNLAAS QLKLDHYRAA LRSCSLVLEH QPDNIKALFR KGKVLAQQGE YSEAIPILRA 360
ALKLEPSNKT IHAELSKLVK KHAAQRSTET ALYRKMLGNP SRLPAKCPGK GAWSIPWKWL 420
FGATAVALGG VALSVVIAAR N 441 
Gene Ontology
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR023114; Elongated_TPR_rpt_dom.
 IPR023566; PPIase_FKBP.
 IPR001179; PPIase_FKBP_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00254; FKBP_C 
SMART
  
PROSITE
 PS50059; FKBP_PPIASE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS